Pediatric Radiology

, Volume 43, Issue 1, pp 55–59

Pediatric brain injury: can DTI scalars predict functional outcome?


DOI: 10.1007/s00247-012-2481-4

Cite this article as:
Xu, D., Mukherjee, P. & Barkovich, A.J. Pediatr Radiol (2013) 43: 55. doi:10.1007/s00247-012-2481-4


Diffusion imaging has made significant inroads into the clinical diagnosis of a variety of diseases by inferring changes in microstructure, namely cell membranes, myelin sheath and other structures that inhibit water diffusion. This review discusses recent progress in the use of diffusion parameters in predicting functional outcome. Studies in the literature using only scalar parameters from diffusion measurements, such as apparent diffusion coefficient (ADC) and fractional anisotropy (FA), are summarized. Other more complex mathematical models and post-processing uses are also discussed briefly.


Pediatric Diffusion MRI Outcome 

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Duan Xu
    • 1
  • Pratik Mukherjee
    • 1
  • A. James Barkovich
    • 1
  1. 1.Department of Radiology and Biomedical ImagingUniversity of California—San FranciscoSan FranciscoUSA

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