Pediatric Radiology

, Volume 42, Issue 9, pp 1145–1148 | Cite as

Rare presentation of BK encephalitis in a child: imaging and pathological findings

  • Jared Green
  • Gaurav Saigal
  • Claudia P. Rojas
  • M. Judith Donovan Post
Case Report


Clinically apparent BK virus infections mostly involve the genitourinary system of immunocompromised patients, particularly those who have undergone renal or bone marrow transplantations. Central nervous system involvement is extremely rare. In this report, we describe the pathologic and MR findings of BK encephalitis in a child. Initial involvement of the brainstem and the cervicomedullary junction was noted that later rapidly progressed to involve other regions of the supratentorial brain parenchyma including the basal ganglia and the thalami as well as the cerebellum.


BK Encephalitis MRI 


  1. 1.
    Ramos E, Drachenberg C, Wali R et al (2009) The decade of polyomavirus BK-associated nephropathy: state of affairs. Transplantation 87:621–630PubMedCrossRefGoogle Scholar
  2. 2.
    Hix JK, Braun W, Isada CM (2004) Delirium in a renal transplant recipient associated with BK virus in the cerebrospinal fluid. Transplantation 78:1407–1408PubMedCrossRefGoogle Scholar
  3. 3.
    Acott PD, Hirsch HH (2007) BK virus infection, replication, and diseases in pediatric kidney transplantation. Pediatr Nephrol 22:1243–1250PubMedCrossRefGoogle Scholar
  4. 4.
    Vallbracht A, Lohler J, Gossman J et al (1993) Disseminated BK type polyomavirus in an AIDS patient associated with central nervous system disease. Am J Pathol 143:29–39PubMedGoogle Scholar
  5. 5.
    Voltz R, Jager G, Seelos K et al (1996) BK virus encephalitis in an immunocompetent patient. Arch Neurol 53:101–103PubMedCrossRefGoogle Scholar
  6. 6.
    Friedman DP, Flanders AE (2006) MR imaging of BK virus encephalitis. AJNR 27:1016–1018PubMedGoogle Scholar
  7. 7.
    Iyer RS, Chaturvedi A, Pruthi S et al (2011) Medication neurotoxicity in children. Pediatr Radiol 41:1455–1464PubMedCrossRefGoogle Scholar
  8. 8.
    Knowles WA, Pipkin P, Andrews N et al (2003) Population based study of antibody to the human polyomaviruses BKV and JCV and the simian polyomavirus SV40. J Med Virol 71:115–123PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Jared Green
    • 1
  • Gaurav Saigal
    • 2
  • Claudia P. Rojas
    • 3
  • M. Judith Donovan Post
    • 2
  1. 1.Department of RadiologyUniversity of Miami Miller School of MedicineMiamiUSA
  2. 2.Department of Radiology, Jackson Memorial HospitalUniversity of Miami Miller School of MedicineMiamiUSA
  3. 3.Department of PathologyUniversity of Miami Miller School of MedicineMiamiUSA

Personalised recommendations