Pediatric Radiology

, Volume 42, Issue 4, pp 402–409

Pediatric MR elastography of hepatic fibrosis: principles, technique and early clinical experience

  • Larry A. Binkovitz
  • Mounif El-Youssef
  • Kevin J. Glaser
  • Meng Yin
  • Anna K. Binkovitz
  • Richard L. Ehman


Numerous pediatric conditions result in hepatic fibrosis. As treatments develop for the underlying disorders, a non-invasive assessment of liver fibrosis would be beneficial as an adjunct or possible replacement for the traditional gold standard, liver biopsy. Magnetic resonance elastography is a noninvasive imaging technique that has been used successfully in adults for identification and assessment of liver fibrosis. This review describes the basic principles of MR elastography as well as the technical aspects specific to children. Clinical pediatric applications, limitations and areas for future research are described.


MR elastography Pediatric Liver MRE 


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Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Larry A. Binkovitz
    • 1
  • Mounif El-Youssef
    • 2
  • Kevin J. Glaser
    • 1
  • Meng Yin
    • 1
  • Anna K. Binkovitz
    • 3
  • Richard L. Ehman
    • 1
  1. 1.Department of RadiologyMayo ClinicRochesterUSA
  2. 2.Pediatric GastroenterologyMayo ClinicRochesterUSA
  3. 3.Macalaster CollegeSt. PaulUSA

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