Pediatric Radiology

, Volume 42, Issue 5, pp 627–631

Anaplastic large cell lymphoma of the esophagus in a pediatric patient

  • Anastasia L. Hryhorczuk
  • Marian H. Harris
  • Sara O. Vargas
  • Edward Y. Lee
Case Report


We report a 3-year-old boy who initially presented with abdominal pain and was subsequently found to have an esophageal perforation. The child did not respond to conservative management, and subsequent lymphadenopathy led to a lymph node biopsy demonstrating an anaplastic lymphoma kinase (ALK)+ anaplastic large cell lymphoma. Esophageal perforation and thickening is most commonly seen in children with a history of esophageal intervention or foreign body/caustic ingestion. Esophageal involvement in children with non-Hodgkin lymphoma (NHL) has not, to our knowledge, been reported in the literature. This case illustrates an unusual presentation of pediatric NHL.


Non-Hodgkin lymphoma Esophagus Pediatric Upper gastrointestinal study CT 


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Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Anastasia L. Hryhorczuk
    • 1
  • Marian H. Harris
    • 2
  • Sara O. Vargas
    • 2
  • Edward Y. Lee
    • 1
  1. 1.Department of RadiologyChildren’s Hospital Boston and Harvard Medical SchoolBostonUSA
  2. 2.Department of PathologyChildren’s Hospital Boston and Harvard Medical SchoolBostonUSA

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