Pediatric Radiology

, Volume 40, Issue 12, pp 1950–1954

Can induced hypothermia be assured during brain MRI in neonates with hypoxic-ischemic encephalopathy?

  • Pia Wintermark
  • Michelle Labrecque
  • Simon K. Warfield
  • Stephanie DeHart
  • Anne Hansen
Technical Innovation

DOI: 10.1007/s00247-010-1816-2

Cite this article as:
Wintermark, P., Labrecque, M., Warfield, S.K. et al. Pediatr Radiol (2010) 40: 1950. doi:10.1007/s00247-010-1816-2

Abstract

Until now, brain MRIs in asphyxiated neonates who are receiving therapeutic hypothermia have been performed after treatment is complete. However, there is increasing interest in utilizing early brain MRI while hypothermia is still being provided to rapidly understand the degree of brain injury and possibly refine neuroprotective strategies. This study was designed to assess whether therapeutic hypothermia can be maintained while performing a brain MRI. Twenty MRI scans were obtained in 12 asphyxiated neonates while they were treated with hypothermia. The median difference between esophageal temperature on NICU departure and return was 0.1°C (range: −0.8 to 0.8°C). We found that therapeutic hypothermia can be safely and reproducibly maintained during a brain MRI. Hypothermia treatment should not prevent obtaining an early brain MRI if clinically indicated.

Keywords

Hypoxic-ischemic encephalopathy Newborn Perinatal asphyxia Hypothermia MRI 

Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Pia Wintermark
    • 1
    • 2
    • 3
  • Michelle Labrecque
    • 1
  • Simon K. Warfield
    • 2
  • Stephanie DeHart
    • 2
  • Anne Hansen
    • 1
  1. 1.Division of Newborn MedicineChildren’s Hospital BostonBostonUSA
  2. 2.Department of RadiologyChildren’s Hospital BostonBostonUSA
  3. 3.Division of Newborn MedicineMontreal Children’s HospitalMontrealCanada

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