Pediatric Radiology

, Volume 40, Issue 7, pp 1281–1284 | Cite as

Acute necrotizing encephalopathy secondary to diphtheria, tetanus toxoid and whole-cell pertussis vaccination: diffusion-weighted imaging and proton MR spectroscopy findings

  • Hale AydinEmail author
  • Esra Ozgul
  • Ahmet Muhtesem Agildere
Case Report


We present a previously healthy 6-month-old boy who was admitted to our hospital with lethargy, hypotonia and focal clonic seizures 6 days following diptheria, tetanus toxoid and whole-cell pertussis vaccination. A diagnosis of acute necrotising encephalopathy was made with the aid of MRI, including diffusion-weighted imaging and proton MR spectroscopy.


Encephalopathy Vaccination MRI Diffusion Spectroscopy Child 


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Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Hale Aydin
    • 1
    Email author
  • Esra Ozgul
    • 1
  • Ahmet Muhtesem Agildere
    • 1
  1. 1.Department of RadiologyBaskent University HospitalAnkaraTurkey

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