Patients with congenital heart disease frequently have complex cardiac and vascular malformations requiring detailed non-invasive diagnostic evaluation including functional parameters.
To evaluate the morphological and functional information provided by a novel 3-D cine steady-state free-precession (SSFP) sequence.
Materials and methods
Twenty consecutive children (mean age 2.2 years, nine boys) were examined using a 1.5-T MR system including 2-D cine gradient-recalled-echo sequences, static 3-D SSFP and 3-D cine SSFP sequences.
Measurement of ventricular structures and volumes showed close agreement between the 3-D cine SSFP sequence and the 2-D cine gradient-recalled-echo and static 3-D SSFP sequences (left ventricular volumes mean difference 1.0–1.9 ml and 8.8–11.4%, respectively; right ventricular volumes 1.7–2.1 ml and 9.9–16.9%, respectively). No systematic bias was observed.
3-D cine MRI provides anatomic as well as functional information with sufficient spatial and temporal resolution in free-breathing infants with congenital heart disease.
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We thank the ‘Stiftung zur Förderung und Erfassung von Zivillisationserkrankungen’ foundation for support of the study and A. Greiser (Siemens Healthcare, Erlangen, Germany) for technical support.
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Seeger, A., Fenchel, M.C., Greil, G.F. et al. Three-dimensional cine MRI in free-breathing infants and children with congenital heart disease. Pediatr Radiol 39, 1333 (2009) doi:10.1007/s00247-009-1390-7
- Cardiac MRI
- 3D cine
- Congenital heart disease