Pediatric Radiology

, 39:1230 | Cite as

Tumefactive intracranial presentation of precursor B-cell acute lymphoblastic leukemia

  • Craig M. Forester
  • Chi L. Braunreiter
  • Hasan Yaish
  • Gary L. HedlundEmail author
  • Zeinab Afify
Case Report


In children, leukemia is the most common malignancy, and approximately 75% of leukemias are acute lymphoblastic leukemia (ALL). Central nervous system leukemia is found at diagnosis in fewer than 5% of children with ALL. Leukemic intracranial masses have been described with acute myeloid leukemia, but ALL presenting as a mass lesion is rare. We describe a unique case of an intracranial confirmed precursor B cell (pre-B) ALL mass in a 13-year-old girl that was diagnosed by brain CT, MRI and cerebral angiography, and confirmed by biopsy. This report details pertinent history and distinguishing imaging features of an intracranial ALL tumefaction.


ALL CNS Leukemia MRS MRI Child 


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Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Craig M. Forester
    • 1
  • Chi L. Braunreiter
    • 2
    • 3
  • Hasan Yaish
    • 2
  • Gary L. Hedlund
    • 4
    Email author
  • Zeinab Afify
    • 2
  1. 1.University of UtahSalt Lake CityUSA
  2. 2.Division of Pediatric Hematology Oncology, Primary Children’s Medical CenterUniversity of UtahSalt Lake CityUSA
  3. 3.Department of Pediatric Hematology OncologyHelen DeVos Children’s HospitalGrand RapidsUSA
  4. 4.Department of Pediatric RadiologyPrimary Children’s Medical CenterSalt Lake CityUSA

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