Pediatric Radiology

, Volume 39, Issue 6, pp 575–585 | Cite as

Central nervous system manifestations of HIV infection in children

  • Reena GeorgeEmail author
  • Savvas Andronikou
  • Jaco du Plessis
  • Anne-Marie du Plessis
  • Ronald Van Toorn
  • Arthur Maydell


Vertically transmitted HIV infection is a major problem in the developing world due to the poor availability of antiretroviral agents to pregnant women. HIV is a neurotrophic virus and causes devastating neurological insults to the immature brain. The effects of the virus are further compounded by the opportunistic infections and neoplasms that occur as a result of the associated immune suppression. This review focuses on the imaging features of HIV infection and its complications in the central nervous system.


Paediatric HIV infection Central nervous system Opportunistic infections Neoplasms 


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Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Reena George
    • 1
    Email author
  • Savvas Andronikou
    • 1
  • Jaco du Plessis
    • 1
  • Anne-Marie du Plessis
    • 1
  • Ronald Van Toorn
    • 2
  • Arthur Maydell
    • 1
  1. 1.Department of Radiology, Tygerberg Academic HospitalUniversity of StellenboschCape TownSouth Africa
  2. 2.Department of Paediatrics and Child Health, Tygerberg Academic HospitalUniversity of StellenboschCape TownSouth Africa

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