Pediatric Radiology

, Volume 38, Issue 7, pp 795–797 | Cite as

Arterial aneurysms and tuberous sclerosis: a classic but little known association

  • Giulio Calcagni
  • Francesco Gesualdo
  • Daniel Tamisier
  • Francis Brunelle
  • Daniel Sidi
  • Phalla Ou
Case Report
First Online:
Received:
Revised:
Accepted:

Abstract

Tuberous sclerosis is a rare autosomal dominant syndrome in which aortic aneurysm is a classic but little known cause of sudden death. We report a 20-month-old boy with tuberous sclerosis and iliofemoral arterial aneurysms. This case highlights the importance of systematic screening for such vascular complications. Multislice CT or MRI is mandatory as a screening and diagnostic tool in this setting to complement US with Doppler examination.

Keywords

Tuberous sclerosis Aorta Aneurysm CT Child 
This is a preview of subscription content, log in to check access.

References

  1. 1.
    Von Recklinghausen F (1862) Ein Herz von einem Neugeborenen, welches mehrere Theils nach aussen, Theils nach den Höhlen prominirende Tumoren trug. Monatschr Geburtsk 21:1–3Google Scholar
  2. 2.
    Bourneville DM (1880) Contributions à l’étude de l’idiote. Sclerose tubereuse des circonvolution cerebrales; idiote et epilepsie hemiplegie. Arch Neurol 1:81–82Google Scholar
  3. 3.
    Weiner DM, Ewalt DH, Roach ES et al (1998) The tuberous sclerosis complex: a comprehensive review. J Am Coll Surg 187:548–561PubMedCrossRefGoogle Scholar
  4. 4.
    Jost CJ, Gloviczki P, Edward WD et al (2001) Aortic aneurysm in children and young adults with tuberous sclerosis: report of two cases and review of the literature. J Vasc Surg 33:639–642PubMedCrossRefGoogle Scholar
  5. 5.
    Beltramello A, Puppini G, Bricolo A et al (1999) Does the tuberous sclerosis complex include intracranial aneurysm? Pediatr Radiol 29:206–211PubMedCrossRefGoogle Scholar
  6. 6.
    Carette MF, Antoine M, Bazelly B et al (2006) Primary pulmonary artery aneurysm in tuberous sclerosis: CT, angiography and pathological study. Eur Radiol 16:2369–2370PubMedCrossRefGoogle Scholar
  7. 7.
    Shepherd CW, Gomez MR, Lie JT et al (1991) Cause of death in patients with tuberous sclerosis. Mayo Clinic Proc 66:792–796Google Scholar
  8. 8.
    Ewalt DH, Sheffield E, Sparagana SP et al (1998) Renal lesion growth in children with tuberous sclerosis complex. J Urol 160:141–145PubMedCrossRefGoogle Scholar
  9. 9.
    Tamisier D, Goutière F, Sidi D et al (1997) Abdominal aortic aneurysm in a child with tuberous sclerosis. Ann Vasc Surg 11:637–639PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • Giulio Calcagni
    • 1
  • Francesco Gesualdo
    • 1
  • Daniel Tamisier
    • 2
  • Francis Brunelle
    • 3
  • Daniel Sidi
    • 1
  • Phalla Ou
    • 1
    • 3
  1. 1.Department of Pediatric Cardiology, Hôpital Necker Enfants Malades, AP-HPUniversity Paris DescartesParisFrance
  2. 2.Department of Pediatric Cardiac Surgery, Hôpital Necker Enfants Malades, AP-HPUniversity Paris DescartesParisFrance
  3. 3.Department of Pediatric Radiology, Hôpital Necker Enfants Malades, AP-HPUniversity Paris DescartesParisFrance

Personalised recommendations