Pediatric Radiology

, Volume 38, Issue 6, pp 694–696 | Cite as

Thickening and enhancement of multiple cranial nerves in conjunction with cystic white matter lesions in early infantile Krabbe disease

  • Lauren A. BeslowEmail author
  • Erin S. Schwartz
  • Carsten G. Bönnemann
Case Report


We present serial MR findings in a child ultimately diagnosed with the early infantile form of Krabbe disease. MR showed typical features of Krabbe disease including cerebellar and brainstem hyperintensity, periventricular and deep white matter hyperintensity, and cerebral atrophy. In addition, the combination of both enlargement and enhancement of multiple cranial nerves in conjunction with unusual cystic lesions adjacent to the frontal horns of the lateral ventricles was previously unreported and expands the spectrum of imaging findings in early Krabbe disease.


Krabbe disease Cranial nerve enlargement Cranial nerve enhancement Cystic lesions 


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Copyright information

© Springer-Verlag 2008

Authors and Affiliations

  • Lauren A. Beslow
    • 1
    Email author
  • Erin S. Schwartz
    • 2
  • Carsten G. Bönnemann
    • 1
  1. 1.Division of NeurologyThe Children’s Hospital of PhiladelphiaPhiladelphiaUSA
  2. 2.Division of NeuroradiologyThe Children’s Hospital of PhiladelphiaPhiladelphiaUSA

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