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Pediatric Radiology

, Volume 36, Issue 10, pp 1105–1107 | Cite as

Liver involvement in Langerhans cell histiocytosis

  • Adelaine Wong
  • Clara L. Ortiz-Neira
  • Walid Abou Reslan
  • Raphael Sharon
  • Alfredo Pinto-Rojas
  • Deepak Kaura
  • Ronald Anderson
Case Report

Abstract

Liver involvement in Langerhans cell histiocytosis (LCH) typically presents with hepatomegaly and other signs of liver dysfunction. We present an 11-month-old child having only minimally elevated liver enzymes as an indication of liver involvement. Using sonography as the initial diagnostic tool followed by MRI, LCH of the liver was revealed. A review of sonographic, CT, MRI and MR cholangiopancreatography findings in liver LCH is presented. We recommend that physicians consider sonography and MRI screening for liver involvement in patients with newly diagnosed LCH, as periportal involvement may be present with little or no liver function abnormality present, as in this patient.

Keywords

Langerhans cell histiocytosis Liver involvement Children Ultrasound CT MRI·MRCP 

Notes

Acknowledgements

We would like to thank Dr. Matthew Butcher, Martin Sherriff and Meg McIvor for their assistance in this case report.

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Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • Adelaine Wong
    • 1
  • Clara L. Ortiz-Neira
    • 1
  • Walid Abou Reslan
    • 1
  • Raphael Sharon
    • 2
  • Alfredo Pinto-Rojas
    • 3
  • Deepak Kaura
    • 1
  • Ronald Anderson
    • 2
  1. 1.Department of Diagnostic ImagingAlberta Children’s HospitalCalgaryCanada
  2. 2.Department of OncologyAlberta Children’s HospitalCalgaryCanada
  3. 3.Department of PathologyAlberta Children’s HospitalCalgaryCanada

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