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Pediatric Radiology

, Volume 35, Issue 6, pp 612–618 | Cite as

Imaging characteristics of primary cranial Ewing sarcoma

  • Wai-Yung LiEmail author
  • Penelope Brock
  • Dawn E. Saunders
Original Article

Abstract

Background: Ewing sarcoma accounts for 10–15% of all childhood malignant bone tumours and is second in prevalence to osteosarcoma. The skull bones are an unusual site of origin of primary Ewing sarcoma in children. Previous reports concentrate on the neurosurgical aspects and relatively good outcome compared to other bone tumours of the calvarium. Reported cases mainly describe the imaging characteristics on CT. Objective: To describe the MRI and CT features of primary cranial Ewing sarcoma. Materials and methods: The neuroimaging of three cases of primary cranial Ewing sarcoma are reviewed. Results: Our three cases show an extra-axial mass that is high attenuation on CT and low signal on T2-weighted MRI. Haemorrhagic components, dural extension and contrast enhancement are also characteristic features. Conclusion: CT attenuation and magnetic resonance signal characteristics reflect sheets of densely packed cells seen in Ewing sarcoma.

Keywords

Skull Tumour Ewing sarcoma CT MRI Children 

References

  1. 1.
    Desai KI, Nadkarni TD, Goel A, et al (2000) Primary Ewing’s sarcoma of the cranium. Neurosurgery 46:62–68; Discussion 68–69Google Scholar
  2. 2.
    Hadfield MG, Quezado MM, Williams RL, et al (2000) Ewing’s family of tumours involving structures related to the central nervous system: a review. Pediatr Dev Pathol 3:203–210Google Scholar
  3. 3.
    Yasuda T, Inagaki T, Yamanouchi Y, et al (2003) A case of primary Ewing’s sarcoma of the occipital bone presenting with obstructive hydrocephalus. Childs Nerv Syst 19:792–799Google Scholar
  4. 4.
    Boumdin H, el Quessar A, Chakir N, et al (2001) Primary Ewing’s sarcoma of the cranial vault. Report of 2 cases (in French). J Neuroradiol 28:200–204Google Scholar
  5. 5.
    Carlotti CG Jr, Drake JM, Hladky JP, et al (1999) Primary Ewing’s sarcoma of the skull in children. Utility of molecular diagnosis, surgery and adjuvant therapies. Pediatr Neurosurg 31:307–315Google Scholar
  6. 6.
    Bhatoe HS, Deshpande GU (1998) Primary cranial Ewing’s sarcoma. Br J Neurosurg 12:165–169Google Scholar
  7. 7.
    Singh P, Jain DP, Kalra N, et al (2002) MR findings of primary Ewing’s sarcoma of greater wing of sphenoid. Australas Radiol 46:409–411Google Scholar
  8. 8.
    Sharma RR, Netalkar A, Lad SD (2000) Primary Ewing’s sarcoma of the greater wing of the sphenoid bone. Br J Neurosurg 14:53–56Google Scholar
  9. 9.
    Freeman MP, Currie CM, Gray GF Jr, et al (1988) Ewing’s sarcoma of the skull with an unusual pattern of reactive sclerosis: MR characteristics. J Comput Assist Tomogr 12:143–146Google Scholar
  10. 10.
    Stiller CA, Bunch KJ (1990) Trends in survival for childhood cancer in Britain diagnosed 1971–85. Br J Cancer 62:806–815Google Scholar
  11. 11.
    Kolb EA, Kushner BH, Gorlick R, et al (2003) Long-term event-free survival after intensive chemotherapy for Ewing’s family of tumors in children and young adults. J Clin Oncol 21:3423–3430Google Scholar
  12. 12.
    Bacci G, Forni C, Longhi A, et al (2004) Long-term outcome for patients with non-metastatic Ewing’s sarcoma treated with adjuvant and neoadjuvant chemotherapies: 402 patients treated at Rizzoli between 1972 and 1992. Eur J Cancer 40:73–83Google Scholar

Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  • Wai-Yung Li
    • 1
    Email author
  • Penelope Brock
    • 2
  • Dawn E. Saunders
    • 1
  1. 1.Departments of RadiologyGreat Ormond Street Hospital for ChildrenLondonUK
  2. 2.Departments of OncologyGreat Ormond Street Hospital for ChildrenLondonUK

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