Improved Left Ventricular Strain and Dyssynchrony After Pulmonary Artery Banding in an Infant with End-Stage Dilated Cardiomyopathy: Insights from Three-Dimensional Speckle Tracking
Pulmonary artery banding may benefit infants with dilated cardiomyopathy. We present the case of an infant with end-stage dilated cardiomyopathy and intractable heart failure who received pulmonary artery banding. Serial follow-up through two-dimensional and three-dimensional echocardiography revealed gradual improvement in the left ventricular ejection fraction and favorable remodeling. The result of three-dimensional speckle tracking suggested that this benefit is associated with improvements in global strain and intraventricular dyssynchrony.
KeywordsDilated cardiomyopathy Pulmonary artery banding Infants Three-dimensional speckle tracking
Compliance with Ethical Standards
Conflict of interest
The authors declare that they have no conflict of interest.
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and was approved by the institutional research committee, and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed parental consent was obtained.
Supplementary file2 (MP4 3841 kb)
Supplementary file3 (MP4 1266 kb)
Supplementary file4 (MP4 578 kb)
Supplementary file5 (MP4 569 kb)
Supplementary file6 (MP4 564 kb)
- 1.Towbin JA, Lowe AM, Colan SD, Sleeper LA, Orav EJ, Clunie S, Messere J, Cox GF, Lurie PR, Hsu D, Canter C, Wilkinson JD, Lipshultz SE (2006) Incidence, causes, and outcomes of dilated cardiomyopathy in children. JAMA 296(15):1867–1876. https://doi.org/10.1001/jama.296.15.1867 CrossRefPubMedGoogle Scholar
- 2.Singh TP, Sleeper LA, Lipshultz S, Cinar A, Canter C, Webber SA, Bernstein D, Pahl E, Alvarez JA, Wilkinson JD, Towbin JA, Colan SD (2009) Association of left ventricular dilation at listing for heart transplant with postlisting and early posttransplant mortality in children with dilated cardiomyopathy. Circ Heart Fail 2:591–598. https://doi.org/10.1161/CIRCHEARTFAILURE.108.839001 CrossRefPubMedGoogle Scholar
- 4.Schranz D, Rupp S, Müller M, Schmidt D, Bauer A, Valeske K, Michel-Behnke I, Jux C, Apitz C, Thul J, Hsu D, Akintürk H (2013) Pulmonary artery banding in infants and young children with left ventricular dilated cardiomyopathy: a novel therapeutic strategy before heart transplantation. J Heart Lung Transplant 32:475–481. https://doi.org/10.1016/j.healun.2013.01.988 CrossRefPubMedGoogle Scholar
- 5.Everitt MD, Sleeper LA, Lu M, Canter CE, Pahl E, Wilkinson JD, Addonizio LJ, Towbin JA, Rossano J, Singh RK, Lamour J, Webber SA, Colan SD, Margossian R, Kantor PF, Jefferies JL, Lipshultz SE, Investigators Pediatric Cardiomyopathy Registry (2014) Recovery of echocardiographic function in children with idiopathic dilated cardiomyopathy: results from the pediatric cardiomyopathy registry. J Am Coll Cardiol 63:1405–1413. https://doi.org/10.1016/j.jacc.2013.11.059 CrossRefPubMedPubMedCentralGoogle Scholar
- 6.Chen CA, Hsiao CH, Wang JK, Lin MT, Wu ET, Chiu SN, Chiu HH, Wu MH (2009) Implication of QRS prolongation and its relation to mechanical dyssynchrony in idiopathic dilated cardiomyopathy in childhood. Am J Cardiol 103:103–109. https://doi.org/10.1016/j.amjcard.2008.08.044 CrossRefPubMedGoogle Scholar