The aim of this study was to evaluate the feasibility, efficacy and safety of transcatheter closure of patent ductus arteriosus (PDA) with the Occlutech duct occluder (ODO) in children. We reviewed the clinical records of 71 patients who underwent percutaneous closure of PDA with an ODO between September 2014 and August 2016. The Occlutech duct occluder was applied to 71 patients during the study period (September 2014–August 2016), and the results were analyzed in this study. Forty-two of the patients were female and 29 male. The median age was 20.5 months (range, 6–194 months) and median weight was 16 kg (range, 6–68 kg). The PDA was classified as type A in 54 patients (76.1%), type E in 14 (19.7%), type C in 2 (2.8%) and type B in 1 (1.4%) based on the Krichenko classification. A standard ODO device was used for the transcatheter closure procedure in 66 patients and the long-shank ODO device in 5. In the echocardiographic measurement of PDA, the median smallest diameter was 2.7 mm (range, 1.5–7.0 mm), and in the angiographic measurement, the median smallest diameter was 2.5 mm (range, 1.5–6.5 mm). All 71 patients underwent successful PDA closure with the ODO. Angiography following the procedure showed complete closure in 47 patients (66.2%), mild residual shunt in 13 patients (18.3%) and a trivial shunt in 11 patients (15.5%). Color flow Doppler echocardiogpaphy at 24 h post-implantation showed that complete closure was achieved in 65 patients (91.5%), and 6 patients (8.5%) had mild residual shunt. All patients (100%) had complete closure at 30 days of follow-up. The results of this study showed that the Occlutech PDA occluder device is safe and effective in the closure of PDA. As the pulmonary artery side of the device is wider than the aortic side, protrusion toward the aortic side and embolization are prevented, but there is residual shunt in the early period, although this residual shunt disappeared after a few months.
Patent ductus arteriosus Children Occlutech duct occluder
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Meki Bilici contributed to the data analysis, drafting the article and statistics. Fikri Demir, Alper Akin, Mehmet Ture and Hasan Balik helped in the data collection, study design and revision of the article. Mahir Kuyumcu contributed to the overall database design, study design and critical revision of the article. Alper Akin and Fikri Demir helped in the study concept and design, data collection and critical revision of the article.
Compliance with Ethical Standards
Conflict of interest
The authors have no commercial or other associations that might pose a conflict of interest in connection to the submitted article. The authors had full control of the design of the study, methods used, outcome parameters, analysis of the data and production of the manuscript.
All procedures performed were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.
Informed consent was obtained from all individual participants included in the study (written consent from parents and/or written assent from children).
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