Pediatric Cardiology

, Volume 37, Issue 2, pp 392–398 | Cite as

Characterization of Cardiac Troponin Elevation in the Setting of Pediatric Supraventricular Tachycardia

  • Jeremy P. MooreEmail author
  • Lisa Arcilla
  • Shuo Wang
  • Michael S. Lee
  • Kevin M. Shannon
Original Article


Cardiac troponin (cTn) is currently considered the gold standard biomarker for detection of myocardial necrosis. Patients with supraventricular tachycardia (SVT) often present with symptoms resulting in cTn assessment; however, there are no data on the results of such testing in childhood. We hypothesized that cTn elevation would be common in the pediatric SVT population and would portend a benign prognosis. A retrospective review of all pediatric patients (≤21 years) presenting with SVT was performed. Clinical and electrocardiographic variables from the emergency department (ED) presentation were reviewed and clinical outcomes during subsequent follow-up assessed. Of 128 patients seen in the ED for SVT, cTn was assessed in 48 (38 %). Of patients with cTn assessment, 14 (29 %) patients demonstrated cTn elevation. Univariate predictors of cTn elevation included presentation with respiratory or gastrointestinal symptoms (50 vs 12 % and 42 vs 9 %; p = 0.008 and p = 0.01, respectively), lower mean arterial blood pressure (73 vs 85 mm Hg, p = 0.009), higher age-adjusted tachycardia rate (z score 9.3 vs 7.2, p < 0.001), and longer tachycardia duration (4.2 vs 1.0 h, p = 0.02). Multivariate logistic regression confirmed the association of age-adjusted tachycardia rate (odds ratio [OR] 3.8 per heart rate z score, confidence interval [CI] 1.9–11.8, p = 0.003) and duration (OR 1.5 per hour, CI 1.1–2.5, p = 0.03). Clinical outcome was excellent with no adverse sequelae during a median of 2.9 years of follow-up. Cardiac Tn elevation is common in the pediatric population presenting with SVT. Episode severity, characterized by respiratory or gastrointestinal symptoms, lower mean blood pressure, and increased tachycardia rate and duration are predictive. Clinical follow-up is favorable.


Cardiac troponin Electrocardiogram Pediatrics Supraventricular tachycardia 



Coronary artery disease


Cardiac troponin




Odds ratio


Supraventricular tachycardia


Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Jeremy P. Moore
    • 1
    Email author
  • Lisa Arcilla
    • 1
  • Shuo Wang
    • 1
  • Michael S. Lee
    • 2
  • Kevin M. Shannon
    • 1
  1. 1.Division of Cardiology, Department of PediatricsUCLA Medical CenterLos AngelesUSA
  2. 2.Division of Cardiology, Department of MedicineUCLA Medical CenterLos AngelesUSA

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