Pediatric Cardiology

, Volume 33, Issue 7, pp 1213–1215 | Cite as

Pharmacologic Cardiac Resynchronization of a 1-Year-Old Boy With Severe Left Ventricular Dysfunction

  • Christian PaechEmail author
  • Patrick Flosdorff
  • Roman Antonin Gebauer
Images in Pediatric Cardiology


Postero-septal accessory pathways (AP) are a rare cause of intraventricular dyssynchrony and severe LV dysfunction in children. Beside the common treatment with radiofrequency ablation of septal substrates we present the case of a successful pharmacologic resynchronization in a 13/12 years old male toddler with Wolff-Parkinson-White syndrome (WPW) and severe LV dysfunction (left ventricular biplane EF of 31 %) due to intraventricular dyssynchrony with septal to posterior wall motion delay (SPWMD) of 350 ms. Interventricular mechanical delay (IVMD) was 65 ms. Using propafenone, pharmacologic cardiac resynchronization could be achieved. Pharmacologic resynchronization should be considered as safe and effective alternative to catheter ablation in very young children.


Wolff-Parkinson-White syndrome Left ventricular dysfunction Cardiac dyssynchrony Resynchronization Pediatrics 

Supplementary material

246_2012_310_MOESM1_ESM.avi (2.9 mb)
Movie 1 Echocardiography with an apical four-chamber view demonstrating asynchronous septal wall motion (AVI 2952 kb)


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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Christian Paech
    • 1
    Email author
  • Patrick Flosdorff
    • 1
  • Roman Antonin Gebauer
    • 1
  1. 1.Department for Pediatric CardiologyUniversity of Leipzig–Heart CenterLeipzigGermany

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