Pediatric Cardiology

, Volume 31, Issue 7, pp 1049–1051 | Cite as

Thoracoabdominal Situs: A Practical Approach Accompanied by a Short History of Descriptive Terms

  • William N. Evans
Original Article


Classification systems for thoracoabdominal situs have been the subject of numerous reports, yet confusion persists. This essay presents an abbreviated historical review of the currently used terms, briefly discusses some of the nomenclature controversies, and proposes a classification system that more closely adheres to the etymology of the descriptors, especially “heterotaxy.”


Cardiac malformations Heterotaxy Medical history 



I thank Dr. Ruben J. Acherman for his suggestions and assistance with the design of Fig. 1.


  1. 1.
    Baillie M (1788) An account of a remarkable transposition of the viscera. Trans R Soc Lond 78:350–363CrossRefGoogle Scholar
  2. 2.
    Charpentier A (1887) Cyclopaedia of obstetrics and gynecology: a practical treatise on obstetrics, vol 3. Wood and Co, New York City, pp 283–284Google Scholar
  3. 3.
    Ivemark B (1955) Implications of agenesis of the spleen on the pathogenesis of cono-truncus anomalies in childhood: analysis of the heart malformations in splenic agenesis syndrome, with fourteen new cases. Acta Paediatr 44(Suppl 104):7–110Google Scholar
  4. 4.
    Küchenmeister F (1883) Die angeborne, vollständige seitliche Verlagerung der Eingeweide des Menschen: (situs viscerum totalis lateralis rarior, solito inversus); für Aerzte und Studirende. Barth, LeipzigGoogle Scholar
  5. 5.
    Ploucquet WG (1797) Initia bibliothecae medico-practicae et chirurgicae realis sive Repertorii medicinae practicae et chirurgiae, vol 8. U-Z. Cotta, Tubingae, p 414Google Scholar
  6. 6.
    Sacks LV, Rifkin IR (1987) Mirror image arrangement of the abdominal organs with a left-sided morphologically normal heart. Br Heart J 58:534–536CrossRefPubMedGoogle Scholar
  7. 7.
    Van Mierop LH, Eisen S, Schiebler GL (1970) The radiographic appearance of the tracheobronchial tree as an indicator of visceral situs. Am J Cardiol 26:432–435CrossRefPubMedGoogle Scholar
  8. 8.
    Ware SM, Belmont JW (2004) ZIC3, CFC1, ACVR2B, and EGAB and the visceral heterotaxies. In: Epstein CJ, Erickson RP, Wynshaw-Boris A (eds) Inborn errors of development: the molecular basis of clinical disorders of morphogenesis. Oxford University Press, Oxford, p 300Google Scholar

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Children’s Heart Center-NevadaLas VegasUSA
  2. 2.University of Nevada School of MedicineLas VegasUSA

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