Pediatric Cardiology

, Volume 31, Issue 6, pp 897–900 | Cite as

Resolution of Dyssynchronous Left Ventricular Failure via Cardiac Resynchronization and Subsequent Radiofrequency Ablation in an Infant With Pre-excitation

  • Maria V. Ilina
  • Dominic J. Abrams
  • Martin D. Lowe
  • Jan MarekEmail author
Case Report


Ventricular pre-excitation causing reversible left ventricular (LV) systolic dysfunction has been reported in adults and children. We describe severe heart failure secondary to ventricular pre-excitation in a 3-month-old girl who presented with echocardiographic evidence of marked intraventricular dyssynchrony. The patient was initially considered for transplantation, but dual chamber left atrioventricular epicardial pacing initiated at 4.5 months of age resulted in a marked clinical and echocardiographic improvement. Five years later, successful radiofrequency ablation resulted in loss of pre-excitation and reversal of LV dyssynchrony, thus allowing pacemaker explantation. To our knowledge, this is one of very few reported cases of pre-excitation–induced cardiomyopathy affecting a young infant and the only case palliated with resynchronization pacing.


Dyssynchrony Pediatric Heart failure Accessory pathway Resynchronization Pre-excitation Speckle tracking echocardiography 


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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Maria V. Ilina
    • 1
  • Dominic J. Abrams
    • 1
    • 3
  • Martin D. Lowe
    • 1
    • 2
  • Jan Marek
    • 1
    Email author
  1. 1.Great Ormond Street HospitalLondonUK
  2. 2.The Heart HospitalLondonUK
  3. 3.St. Bartholomew’s Hospital LondonUK

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