Pediatric Cardiology

, Volume 29, Issue 2, pp 352–358 | Cite as

QT Dispersion and Diastolic Functions in Differential Diagnosis of Primary Mitral Valve Prolapse and Rheumatic Mitral Valve Prolapse

  • Barıs Guven
  • Ayse Guler Eroglu
  • Kadir Babaoglu
  • Tevfik Demir
  • Alper Güzeltas
  • Funda Oztunc
  • Levent Saltik
Original
First Online:
Received:
Accepted:

Abstract

There is no specific criteria established to guide physicians in the differential diagnosis of primary mitral valve prolapse (MVP) and rheumatic MVP. Previous studies suggested that history and pathology of mitral valve could be helpful in differential diagnosis of MVP. The aim of this study was to evaluate the value of QT interval, QT dispersion, and diastolic function in differential diagnosis of MVP. We examined electrocardiographies and echocardiographies of 24 primary MVP patients, 20 rheumatic MVP patients, and 21 healthy subjects. MVP was defined as superior displacement of the mitral leaflets more than 2 mm into the left atrium during systole. QT dispersion was significantly higher in primary MVP patients (71 ± 13.5 ms, p < 0.01). Maximum QT dispersion value in rheumatic MVP patients was 55 ms. E and A velocity values which show ventricular early and late diastolic filling, were lower in primary MVP patients (p < 0.01). There was no difference in the heart rate corrected QT interval values between the primary MVP patients (397 ± 28.1), rheumatic MVP patients (403 ± 23.8) and healthy children (404 ± 15.8; p > 0.05). Our findings may indicate that QT dispersion can be used as a parameter for differential diagnosis of primary MVP and rheumatic MVP. Further studies are needed to identify a cut-off point of QT dispersion.

Keywords

Mitral Valve Mitral Regurgitation Diastolic Function Rheumatic Fever Mitral Valve Prolapse 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Notes

Acknowledgment

The present work was supported by the Research Fund of Istanbul University. Project No. UDP-612/02082005.

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Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Barıs Guven
    • 1
  • Ayse Guler Eroglu
    • 2
  • Kadir Babaoglu
    • 2
  • Tevfik Demir
    • 2
  • Alper Güzeltas
    • 2
  • Funda Oztunc
    • 2
  • Levent Saltik
    • 2
  1. 1.Department of PediatricsIstanbul University Cerrahpaşa Medical FacultyIstanbulTurkey
  2. 2.Division of Pediatric Cardiology, Department of PediatricsIstanbul University Cerrahpaşa Medical FacultyIstanbulTurkey

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