Organotin Compounds, Including Butyltins and Octyltins, in House Dust from Albany, New York, USA

  • Kurunthachalam Kannan
  • Shin Takahashi
  • Naohiro Fujiwara
  • Hazuki Mizukawa
  • Shinsuke Tanabe


Organotin compounds (OTs) have been used in a wide variety of consumer products. Despite this, very few studies have reported the occurrence of OTs in house dust or exposure of humans to OTs through the ingestion of house dust. In the present study, concentrations of monobutyltin (MBT), dibutyltin (DBT), tributyltin (TBT), monooctyltin (MOT), dioctyltin (DOT), trioctyltin (TOT), diphenyltin (DPT), and triphenyltin (TPT) were measured in dust collected from 24 houses in Albany, New York, USA. In addition, a few household products, such as wallpaper, floor tile, vinyl window blinds, and handbags were analyzed for the presence of OTs. Organotins were found in all of the house dust samples analyzed, and total OT concentrations varied from 390 to 28,000 ng/g (mean ± SD: 6700 ± 6200; median: 5000). Relative abundances of OTs in house dust were in the order MBT >MOT >DBT >DOT >TBT. TOT, DPT, and TPT were not found in any of the samples at concentrations above their corresponding detection limits. MBT accounted for, on average, 51% of the total OT concentrations. Mean concentrations of total OTs found in house dust samples from our study were two to five times higher than concentrations that have been reported for dust samples from several European countries. Calculations indicate that dust ingestion by children account for, on average, 15–18% of the tolerable daily intake proposed by the World Health Organization (WHO). The estimated rates of OT intake by children via dust ingestion were, on average, eightfold higher than the intake rates calculated for adults. Household products, such as wallpaper, contained total OT concentrations as high as 780,000 ng/g.


Dust House Dust Dust Sample Organotin Compound Tolerable Daily Intake 
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We thank Ms. Keiko Higaki for assistance with chemical analysis. This research was supported in part by the waste management research grants (K2121 and K2129) from the Ministry of the Environment, Japan, the Grants-in-Aid for Scientific Research (S) (No. 20221003) from Japan Society for the Promotion of Science (JSPS) and Global COE Program from the Japanese Ministry of Education, Culture, Sports, Science and Technology, and in part by a grant from the CDC (Centers for Disease Control and Prevention, Atlanta, USA) on Expanding New York State Public Health Laboratory Capability and Capacity to Conduct Biomonitoring (1U38EH000464-01) to Wadsworth Center.


  1. Al Bitar F (2004) Hazardous chemicals in Belgian house dust. Greenpeace, BelgiumGoogle Scholar
  2. Allsopp A, Santillo D, Johnston P (2000) Hazardous chemicals in PVC flooring. Greenpeace Research Laboratories Technical Note 14/00, Greenpeace, BelgiumGoogle Scholar
  3. Alzieu C, Michel P, Tolosa I, Bacci E, Mee LD, Readman JW (1991) Organotin compounds in the Mediterranean: a continuing cause for concern. Marine Environ Res 32:261–270CrossRefGoogle Scholar
  4. Antizar-Ladislao B (2008) Environmental levels, toxicity and human exposure to tributyltin (TBT)-contaminated marine environment. A review. Environ Int 34:292–308CrossRefGoogle Scholar
  5. Azenha M, Vasconcelos MT (2002) Butyltin compounds in Portuguese wines. J Agric Food Chem 50:2713–2716CrossRefGoogle Scholar
  6. Belfroid AC, Purperhart M, Ariese F (2000) Organotin levels in seafood. Marine Pollut Bull 40:226–232CrossRefGoogle Scholar
  7. Bryan GW, Gibbs PE, Hummerstone LG, Burt GR (1986) The decline of the gastropod Nucella lapillus around southwest England: evidence for the effect of tributyltin from antifouling paints. J Marine Biol Assoc UK 66:611–640CrossRefGoogle Scholar
  8. Champ MA (2000) A review of organotin regulatory strategies, pending actions, related costs and benefits. Sci Total Environ 258:21–71CrossRefGoogle Scholar
  9. Costner P, Thorpe B, McPherson A (2005) Sick of dust: chemicals in common products—a needless health risk in our homes. Safer Products ProjectGoogle Scholar
  10. EU-SCOOP (2006) Revised assessment of the risks to health and the environment associated with the use of the four organotin compounds TBT, DBT, DOT and TPT. Directorate General Health and Consumer Protection. Accessed Feb 2010)
  11. Fent K (1996) Ecotoxicology of organotin compounds. Crit Rev Toxicol 26:1–117CrossRefGoogle Scholar
  12. Forsyth DS, Weber D, Barlow L (1992a) The determination of organotin compounds in fruit juices using gas chromatography-atomic absorption spectrometry. Appl Organomet Chem 6:579–585CrossRefGoogle Scholar
  13. Forsyth DS, Weber D, Cle′roux C (1992b) Determination of butyltin, cyclohexyltin and phenyltin compounds in beers and wines. Food Addit Contam 9:161–169Google Scholar
  14. Fromme H, Mattulat A, Lahrz T, Rüden H (2005) Occurrence of organotin compounds in house dust in Berlin (Germany). Chemosphere 58:1377–1383CrossRefGoogle Scholar
  15. Johnson-Restrepo B, Kannan K (2009) An assessment of sources and pathways of human exposure to polybrominated diphenyl ethers in the United States. Chemosphere 76:542–548CrossRefGoogle Scholar
  16. Jones-Lepp TL, Varner KE, Hilton BA (2001) Speciation and detection of organotins from PVC pipe by micro-liquid chromatography-electrospray ion trap mass spectrometry. Appl Organomet Chem 15:933–938CrossRefGoogle Scholar
  17. Kannan K, Falandysz J (1997) Butyltin residues in sediment, fish, fish-eating birds, harbour porpoise and human tissues collected from the Polish coast of the Baltic Sea. Marine Pollut Bull 34:203–207CrossRefGoogle Scholar
  18. Kannan K, Tanabe S (2008) Global contamination by organotin compounds. In: Arai T et al (eds) Ecotoxicology of Antifouling Biocides. Springer-Verlag, New York, pp 39–60Google Scholar
  19. Kannan K, Tanabe S, Iwata H, Tatsukawa R (1995) Butyltins in muscle and liver of fish collected from certain Asian and Oceanian countries. Environ Pollut 90:279–290CrossRefGoogle Scholar
  20. Kannan K, Corsolini S, Focardi S, Tanabe S, Tatsukawa R (1996) Accumulation pattern of butyltin compounds in dolphin, tuna and shark collected from Italian coastal waters. Arch Environ Contam Toxicol 31:19–23CrossRefGoogle Scholar
  21. Kannan K, Senthilkumar K, Loganathan BG, Takahashi S, Odell DK, Tanabe S (1997) Elevated levels of tributyltin and its breakdown products in bottlenose dolphins (Tursiops truncatus) found stranded along the US Atlantic and Gulf coasts. Environ Sci Technol 31:296–301CrossRefGoogle Scholar
  22. Kannan K, Senthilkumar K, Giesy JP (1999) Occurrence of butyltin compounds in human blood. Environ Sci Technol 33:1776–1779CrossRefGoogle Scholar
  23. Lioy P, Freeman N, Millette J (2002) Dust: a metric for use in residential and building exposure assessment and source characterization. Environ Health Perspect 110:969–983Google Scholar
  24. Liu J-Y, Jiang G-B (2002) Survey of the presence of butyltin compounds in Chinese alcoholic beverages, determined by using headspace solid-phase microextraction coupled with gas chromatography-flame photometric detection. J Agric Food Chem 50:6683–6687CrossRefGoogle Scholar
  25. Mino Y, Amano F, Yoshioka T, Konishi Y (2008) Determination of organotins in human breast milk by gas chromatography with flame photometric detection. J Health Sci 54:224–228CrossRefGoogle Scholar
  26. Nielsen JB, Strand J (2002) Butyltin compounds in human liver. Environ Res Section A 88:129–133CrossRefGoogle Scholar
  27. Rantakokko P, Kuningas T, Saastamoine K, Vartiainen T (2006) Dietary intake of organotin compounds in Finland: a market-basket study. Food Addit Contam A 23:749–756CrossRefGoogle Scholar
  28. Rantakokko P, Turunen A, Verkasalo PK, Kiviranta H, Männistö S, Vartiainen T (2008) Blood levels of organotin compounds and their relation to fish consumption in Finland. Sci Total Environ 399:90–95CrossRefGoogle Scholar
  29. Roberts JW, Wallace LA, Camann DE, Dickey P, Gilbert SG, Lewis RG, Takaro TK (2009) Monitoring and reducing exposure of infants to pollutants in house dust. Rev Environ Contam Toxicol 201:1–39CrossRefGoogle Scholar
  30. RPA (2005) Risk assessment studies on targeted consumer applications of certain organotin compounds. Report of the European CommissionGoogle Scholar
  31. Sadiki AI, Williams DT (1999) A study on organotin levels in Canadian drinking water distributed through PVC pipes. Chemosphere 38:1541–1548CrossRefGoogle Scholar
  32. Santillo D, Labunska I, Davidson H, Johnston P, Strutt M, Knowles O (2003) Consuming chemicals: hazardous chemicals in house dust as an indicator of chemical exposure in the home. Greenpeace Research Laboratories, BelgiumGoogle Scholar
  33. Snoeij NJ, Penninks AH, Seinen W (1987) Biological activity of organotin compounds: an overview. Environ Res 44:335–353CrossRefGoogle Scholar
  34. Sousa A, Laranjeiro F, Takahashi S, Tanabe S, Barroso CM (2009) Imposex and organotin prevalence in a European post-legislative scenario: temporal trends from 2003 to 2008. Chemosphere 77:563–577CrossRefGoogle Scholar
  35. Takahashi S, Mukai H, Tanabe S, Sakayama K, Miyazaki T, Masuno H (1999) Butyltin residues in livers of humans and wild terrestrial mammals and in plastic products. Environ Pollut 106:213–218CrossRefGoogle Scholar
  36. Tsuda T, Inoue T, Kojima M, Aoki S (1995) Daily intakes of tributyltin and triphenyltin compounds from meals. J AOAC Int 78:941–943Google Scholar
  37. USEPA (1997) Toxicological review. Tributyltin oxide. Integrated risk information system. Washington, DC.
  38. Whalen MM, Loganathan BG, Kannan K (1999) Immunotoxicity of environmentally relevant concentrations of butyltins on human natural killer (NK) cells in vitro. Environ Res 81:108–116CrossRefGoogle Scholar
  39. WHO (1999) Tributyltin oxide. Concise international chemical assessment document 14. WHO, GenevaGoogle Scholar
  40. Yamada S, Fujii Y, Mikami E, Kawamura N, Hayakawa J, Aoki K, Fukaya M, Terao C (1993) Small-scale survey of organotin compounds in household commodities. J AOAC Int 76:436–441Google Scholar

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Kurunthachalam Kannan
    • 1
  • Shin Takahashi
    • 2
  • Naohiro Fujiwara
    • 2
  • Hazuki Mizukawa
    • 2
  • Shinsuke Tanabe
    • 2
  1. 1.New York State Department of Health, and Department of Environmental Health SciencesWadsworth Center, State University of New York at AlbanyAlbanyUSA
  2. 2.Center for Marine Environmental Studies (CMES)Ehime UniversityMatsuyamaJapan

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