Urological Research

, Volume 37, Issue 3, pp 133–139 | Cite as

Effects of calcium supplementation on body weight reduction in overweight calcium stone formers

  • Viviane Barcellos Menon
  • Alessandra Calábria Baxmann
  • Leila Froeder
  • Lígia Araújo Martini
  • Ita Pfeferman Heilberg
Original Paper


A randomized, placebo-controlled trial was conducted in overweight calcium stone-forming (CSF) patients, to evaluate the effect of calcium supplementation associated with a calorie-restricted diet on body weight (BW) and fat reduction and its potential changes upon serum and urinary parameters. Fifteen patients were placed on a hypocaloric diet for 3 months, supplemented with either calcium carbonate (CaCO3, n = 8) or placebo (n = 7), 500 mg bid. Blood and 24-h urine samples were collected and body composition was assessed at baseline and after the intervention. At the end of the study, final BW was significantly lower vs baseline in both CaCO3 (74 ± 14 vs. 80 ± 14 kg, P = 0.01) and placebo groups (80 ± 10 vs. 87 ± 9 kg, P = 0.02) but the mean percentage of loss of body weight and body fat did not differ between CaCO3 and placebo (7.0 ± 2.0 vs. 8.0 ± 3.0%, P = 0.40 and 13.0 ± 7.0 vs. 13.0 ± 10.0%; P = 0.81, respectively). After CaCO3 or placebo, no significant differences versus baseline were observed for urinary parameters in both CaCO3 and placebo, except for a higher mean urinary citrate in placebo group. These data suggest that increasing calcium intake by calcium carbonate supplementation did not contribute to a further reduction of BW and fat in overweight CSF patients submitted to a hypocaloric diet nor altered urinary lithogenic parameters.


Calcium intake Weight loss Kidney stones Vitamin D 


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Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Viviane Barcellos Menon
    • 1
  • Alessandra Calábria Baxmann
    • 1
  • Leila Froeder
    • 1
  • Lígia Araújo Martini
    • 3
  • Ita Pfeferman Heilberg
    • 2
  1. 1.Nutrition ProgramUniversidade Federal de São PauloSão PauloBrazil
  2. 2.Nephrology DivisionUniversidade Federal de São PauloSão PauloBrazil
  3. 3.Nutrition DepartmentUniversidade de São PauloSão PauloBrazil

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