Urological Research

, Volume 34, Issue 2, pp 131–133

Impact of dietary habits on stone incidence



Changes in dietary habits and lifestyle are suggested to contribute markedly to the rise in the prevalence and incidence of urolithiasis during the past decades. Insufficient fluid intake and diets rich in animal protein are considered to be important determinants of stone formation. Overweight and associated dietary pattern additionally contribute to the increasing incidence and prevalence of stone disease. Reduction of overweight through extreme fasting or high-protein weight-loss diets, e.g. Atkins diet, also appear to affect stone formation. Although there is evidence that changes in dietary habits can reduce urinary risk factors and the risk of stone formation, further randomized controlled clinical trials are necessary to evaluate long-term effects of dietary interventions on stone disease.


Dietary habits Urinary stone disease Urolithiasis Dietary risk factors 


  1. 1.
    Yoshida O, Okada Y (1990) Epidemiology of urolithiasis in Japan: a chronological and geographical study. Urol Int 45:104PubMedCrossRefGoogle Scholar
  2. 2.
    Trinchieri A, Coppi F, Montanari E, Del Nero A, Zanetti G, Pisani E (2000) Increase in the prevalence of symptomatic upper urinary tract stones during the last ten years. Eur Urol 37:23CrossRefPubMedGoogle Scholar
  3. 3.
    Stamatelou KK, Francis ME, Jones CA, Nyberg LM, Curhan GC (2003) Time trends in reported prevalence of kidney stones in the United States: 1976–1994. Kidney Int 63:1817CrossRefPubMedGoogle Scholar
  4. 4.
    Hesse A, Brändle E, Wilbert D, Köhrmann KU, Alken P (2003) Study on the prevalence and incidence of urolithiasis in Germany comparing the years 1979 vs. 2000. Eur Urol 44:709CrossRefPubMedGoogle Scholar
  5. 5.
    Curhan GC, Willett WC, Rimm EB, Stampfer MJ (1993) A prospective study of dietary calcium and other nutrients and the risk of symptomatic kidney stones. N Engl J Med 328:833CrossRefPubMedGoogle Scholar
  6. 6.
    Curhan GC, Willett WC, Speizer FE, Spiegelman D, Stampfer MJ (1997) Comparison of dietary calcium with supplemental calcium and other nutrients as factors affecting the risk for kidney stones in women. Ann Intern Med 126:497PubMedGoogle Scholar
  7. 7.
    Borghi L, Meschi T, Amato F, Briganti A, Novarini A, Giannini A (1996) Urinary volume, water and recurrences in idiopathic calcium nephrolithiasis: a 5-year randomized prospective study. J Urol 155:839CrossRefPubMedGoogle Scholar
  8. 8.
    Curhan GC, Willett WC, Rimm EB, Spiegelman D, Stampfer MJ (1996) Prospective study of beverage use and the risk of kidney stones. Am J Epidemiol 143:240PubMedGoogle Scholar
  9. 9.
    Rodgers A (1999) Effect of cola consumption on urinary biochemical and physicochemical risk factors associated with calcium oxalate urolithiasis. Urol Res 27:77CrossRefPubMedGoogle Scholar
  10. 10.
    Curhan GC, Willett WC, Speizer FE, Stampfer MJ (1998) Beverage use and risk for kidney stones in women. Ann Intern Med 128:534PubMedGoogle Scholar
  11. 11.
    Goldfarb DS, Fischer ME, Keich Y, Goldberg J (2005) A twin study of genetic and dietary influences on nephrolithiasis: a report from the Vietnam Era Twin (VET) Registry. Kidney Int 67:1053CrossRefPubMedGoogle Scholar
  12. 12.
    Massey LK, Sutton RAL (2004) Acute caffeine effects on urine composition and calcium kidney stone risk in calcium stone formers. J Urol 172:555CrossRefPubMedGoogle Scholar
  13. 13.
    Robertson WG, Peacock M, Hodgkinson A (1979) Dietary changes and the incidence of urinary calculi in the UK between 1958 and 1976. J Chronic Dis 32:469CrossRefPubMedGoogle Scholar
  14. 14.
    Barzel US, Massey LK (1998) Excess dietary protein can adversely affect bone. J Nutr 128:1051PubMedGoogle Scholar
  15. 15.
    Schuette SA, Hegsted M, Zemel MB, Linkswiler HM (1981) Renal acid, urinary cyclic AMP, and hydroxyproline excretion as affected by level of protein, sulfur amino acid, and phosphorus intake. J Nutr 111:2106PubMedGoogle Scholar
  16. 16.
    Brändle E, Hesse A, Hautmann RE (1995) Effect of protein on renal excretion of lithogenic substances and glomerular filtration rate—new pathophysiological aspects for the lithogenic action of dietary protein. In: Rao PN, Kavanagh JR, Tiselius HG (eds) Urolithiasis: consensus and controversies. University Hospital, Manchester 265 ppGoogle Scholar
  17. 17.
    Giannini S, Nobile M, Sartori L, Carbonare LD, Ciuffreda M, Corrò P, D’Angelo A, Calò L, Crepaldi G (1999) Acute effects of moderate dietary protein restriction in patients with idiopathic hypercalciuria and calcium nephrolithiasis. Am J Clin Nutr 69:267PubMedGoogle Scholar
  18. 18.
    Borghi L, Schianchi T, Meschi T, Guerra A, Allegri F, Maggiore U, Novarini A (2002) Comparison of two diets for the prevention of recurrent stones in idiopathic hypercalciuria. N Engl J Med 346:77CrossRefPubMedGoogle Scholar
  19. 19.
    Choi HK, Atkinson K, Karlson EW, Willett W, Curhan G (2004) Purine-rich foods, dairy and protein intake, and the risk of gout in men. N Engl J Med 350:1093CrossRefPubMedGoogle Scholar
  20. 20.
    Siener R, Glatz S, Nicolay C, Hesse A (2004) The role of overweight and obesity in calcium oxalate stone formation. Obes Res 12:106PubMedCrossRefGoogle Scholar
  21. 21.
    Taylor EN, Stampfer MJ, Curhan GC (2005) Obesity, weight gain, and the risk of kidney stones. JAMA 293:455CrossRefPubMedGoogle Scholar
  22. 22.
    Maalouf NM, Sakhaee K, Parks JH, Coe FL, Adams-Huet B, Pak CYC (2004) Association of urinary pH with body weight in nephrolithiasis. Kidney Int 65:1422CrossRefPubMedGoogle Scholar
  23. 23.
    Gillen DL, Worcester EM, Coe FL (2005) Decreased renal function among adults with a history of nephrolithiasis: a study of NHANES III. Kidney Int 67:685CrossRefPubMedGoogle Scholar
  24. 24.
    Reddy ST, Wang CY, Sakhaee K, Brinkley L, Pak CYC (2002) Effect of low-carbohydrate high-protein diets on acid–base balance, stone-forming propensity, and calcium metabolism. Am J Kidney Dis 40:265CrossRefPubMedGoogle Scholar
  25. 25.
    Siener R, Schade N, Nicolay C, von Unruh GE, Hesse A (2005) The efficacy of dietary intervention on urinary risk factors for stone formation in recurrent calcium oxalate stone patients. J Urol 173:1601CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  1. 1.Department of UrologyUniversity of BonnBonnGermany

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