Advertisement

Journal of Molecular Evolution

, Volume 52, Issue 3, pp 260–274 | Cite as

Vertebrate LTR Retrotransposons of the Tf1/Sushi Group

  • Margaret  Butler
  • Timothy  Goodwin
  • Matthew  Simpson
  • Monica  Singh
  • Russell  Poulter

Abstract.

LTR retrotransposons of the Tf1/sushi group from a diversity of vertebrates, including fish, amphibians, and mammals (humans, mice, and others), are described as full-length or partial elements. These elements are compared, and the mechanisms involved in self-priming of reverse transcriptase and programmed phase shifting are inferred. Evidence is presented that in mammals these elements are still transcriptionally active and are represented as proteins. This suggests that members of the Tf1/sushi group are present as functional elements (or incorporated as partial elements into host genes) in diverse vertebrate lineages.

Key words: Vertebrate LTR retrotransposon — Programmed phase shifting — Reverse transcriptase self-priming — Mammalian retrotransposon 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Copyright information

© Springer-Verlag New York Inc. 2001

Authors and Affiliations

  • Margaret  Butler
    • 1
  • Timothy  Goodwin
    • 1
  • Matthew  Simpson
    • 1
  • Monica  Singh
    • 1
  • Russell  Poulter
    • 1
  1. 1.Department of Biochemistry, University of Otago, Dunedin, New ZealandNZ

Personalised recommendations