Versatility of dermal regeneration templates in the treatment of burn sequelae

  • Luís Mata Ribeiro
  • Rafaela Serras
  • Íris Brito
  • Ana Guerra
  • Nuno Maria
  • Joaquim Bexiga
  • Maria Manuel Mendes
Original Paper



The management of burn sequelae is a major challenge for every plastic surgeon. The benefits of Integra® Dermal Regeneration Template in the management of burn injuries have been well documented but there is still a paucity of data regarding its use in reconstructive procedures. The aim of this study is to evaluate its effectiveness in the surgical treatment of post-burn scars.


We performed a retrospective review of burn patients with major burn sequelae treated with Integra® at our hospital during 2016–2017 period. A modified Vancouver Scar Scale (mVSS) was used to provide a more objective measurement of burn scars. All patients were submitted to a two-stage procedure. The first one consisted in complete excision of the lesions and implantation of Integra and the second one in resurfacing the neodermis with a split thickness skin graft.


The average wound size covered with Integra was 741.6 cm2. Follow-up ranged from 9 to 16 months. There were no early complications. In all cases, we achieved satisfactory cosmetic results with significant improvements in functionality and quality of life. mVSS score post-op was significantly lower than pre-op in all patients.


Our results suggest that Integra is a very versatile tool for the treatment of burn sequelae. It yields good cosmetic and functional results in most cases with very little donor site morbidity. We believe that Integra should be viewed as one of the best current options for reconstructive procedures in burn patients.

Level of Evidence: Level IV, therapeutic study.


Integra Dermal template Scar contracture Burn sequelae Keloid 


Compliance with ethical standards


This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

Conflicts of interest

Luís Mata Ribeiro, Rafaela Serras, Íris Brito, Ana Guerra, Nuno Maria, Joaquim Bexiga and Maria Manuel Mendes declare that they have no conflict of interest.

Informed consent

Informed consent for medical photographies and medical records was obtained from all individual participants included in the study.

Ethical approval

For this type of retrospective study formal consent from a local ethics committee is not required.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Plastic and Reconstructive SurgeryHospital São José (Centro Hospitalar Lisboa Central)LisbonPortugal
  2. 2.Department of Plastic and Reconstructive SurgeryCentro Hospitalar e Universitário de CoimbraCoimbraPortugal

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