Sentinel lymph node mapping for patients with Merkel cell carcinoma—experience of 5 years
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Merkel cell carcinoma (MCC) is a rare, highly malignant carcinoma of the neuroendocrinological system (Bayrou et al., J Am Acad Dermatol 24:198–207, 1992). It is a fast-growing, aggressive tumor with a high rate of local recurrence and early metastases. A radical surgical procedure is the therapy of choice. In case of lymph node metastases, regional lymphadenectomy is mandatory. Sentinel lymph node (SLN) mapping is a standard diagnostic technique to detect micrometastases in certain patients with malignant melanoma and breast cancer. The question is, can the SLN technique provide information as a prognostic factor and can the prognosis of the MCC be improved by detecting micrometastases in SLN at an early stage?
KeywordsMerkel cell carcinoma Sentinel lymph node mapping
- 5.Blom A, Kolb F, Lumbroso J, Duvillard P, Mamelle G, Ricard M, Spatz A, Petrow P, Margulis A, Avril MF (2003) Significance of sentinel lymph node biopsy in Merkel cell carcinoma. Ann Dermatol Venereol 130(4):17–22Google Scholar
- 8.Meeuwissen JA, Bourne RG, Kearsley JH (1995) The importance of postoperative radiation therapy in the treatment of Merkel cell carcinoma. Int J Radiat Oncol Biol Phys 31:325–331Google Scholar