Neuroradiology

, Volume 43, Issue 5, pp 345–352

Proton magnetic resonance spectroscopy in brain tumours: clinical applications

  • I. M. Burtscher
  • S. Holtås
REVIEW

Abstract

Parallel to the rapid development of clinical MRI, MR spectroscopy (MRS) has, after starting as an analytical tool used in chemistry and physics, evolved to a noninvasive clinical examination. Most common neuroradiological diagnostic indications for MRS are functional inborn errors, neonatal hypoxia, ischaemia, metabolic diseases, white matter and degenerative diseases, epilepsy, inflammation, infections and intracranial neoplasm. Compared to CT and MRI, well-established morphological diagnostic tools, MRS provides information on the metabolic state of brain tissue. We review the clinical impact of MRS in diagnosis of tumours and their differentiation from non-neoplastic lesions.

Key words Magnetic resonance spectroscopy Brain tumours 

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Copyright information

© Springer-Verlag Berlin Heidelberg 2001

Authors and Affiliations

  • I. M. Burtscher
    • 1
  • S. Holtås
    • 1
  1. 1.Department of Diagnostic Radiology, University Hospital, 22 185 Lund, Sweden e-mail: isabella.burtscher@drad.lu.se Tel.: + 46-46-17 10 00 Fax: + 46-46-17 18 37SE

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