, Volume 61, Issue 1, pp 97–102 | Cite as

Submaximal primary angioplasty for symptomatic intracranial atherosclerosis: peri-procedural complications and long-term outcomes

  • Guangge Peng
  • Jingyu Zhang
  • Baixue Jia
  • Ziqi Xu
  • Dapeng Mo
  • Ning Ma
  • Feng Gao
  • Zhongrong MiaoEmail author
Interventional Neuroradiology



The aim of our study is to report the peri-procedural complications and long-term stroke recurrent rate of symptomatic intracranial atherosclerosis (ICAS) patients who underwent submaximal primary angioplasty.


This is a retrospective analysis of consecutive patients in a single center who underwent submaximal primary angioplasty between January 1, 2012 and December 31, 2015. The peri-procedural complications and long-term outcomes are reported.


Primary angioplasty was successfully performed in 129 patients (97.0%). The mean degree of pre-procedural stenosis was 81.9 ± 10.2%, and the degree of residual stenosis was 40.7 ± 19.1%. There were nine (6.8%) peri-procedural complications within 30 days, including seven ischemic strokes, one subarachnoid hemorrhage, and one asymptomatic intracerebral hemorrhage. None of them resulted in death. One-year follow-up was available in 122 patients (91.7%). Three more ischemic strokes (2.3%) which were in the territory of the treated artery occurred between 30 days and 1 year. The 1-year stroke and death rate was 9.0%, including peri-procedural stroke. Kaplan-Meier analysis showed a 3-year stroke-free survival of 87.2%.


Submaximal primary angioplasty can be performed with a low peri-procedural complication rate and relatively good clinical outcome at long-term follow-up for symptomatic ICAS patients.


Atherosclerosis Angioplasty Intervention Stroke 


Compliance with ethical standards


This work was funded by Beijing High-Level Personnel Funds (Grant no. 2013-2-19) to ZM and the National Natural Science Foundation of China (Grant no. 81371290) to ZM.

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in the studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. For this type of study formal consent is not required.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Guangge Peng
    • 1
    • 2
  • Jingyu Zhang
    • 1
    • 2
  • Baixue Jia
    • 1
    • 2
  • Ziqi Xu
    • 3
  • Dapeng Mo
    • 1
    • 2
  • Ning Ma
    • 1
    • 2
  • Feng Gao
    • 1
    • 2
  • Zhongrong Miao
    • 1
    • 2
    Email author
  1. 1.Department of Interventional Neuroradiology, Beijing Tiantan HospitalCapital Medical UniversityBeijingChina
  2. 2.National Clinical Research Center for Neurological Diseases, Center of Stroke, Beijing Key Laboratory of Translational Medicine for Cerebrovascular DiseasesBeijing Institute for Brain DisordersBeijingChina
  3. 3.The First Affiliated Hospital of Zhejiang UniversityHangzhouChina

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