Guillain Barré syndrome-related posterior reversible encephalopathy syndrome
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Reversible posterior encephalopathy syndrome (PRES), first described by Hinchey et al. in 1996, is a neurological condition characterized by headache, nausea/vomiting, seizures, visual field disturbances, altered sensorium, decreased alertness, and focal neurological deficits. The main finding of PRES on magnetic resonance imaging (MRI) is usually bilateral, often symmetric, posterior white matter hyperintensity on T2 weighted images, consistent with vasogenic edema . PRES can develop in association with a variety of conditions that may cause acute alteration of blood pressure such as preeclampsia/eclampsia, as well exposure to chemotherapeutic drugs. Concurrent occurrence of Guillain-Barré syndrome (GBS) with PRES is a rare entity and only a few cases have been reported. GBS is considered a post-infectious syndrome triggered by different organisms or illnesses. The pathophysiology of the disease is most likely due to molecular mimicry.
We report the unique case of PRES in...
KeywordsPediatric Intensive Care Unit White Matter Hyperintensity Posterior Reversible Encephalopathy Syndrome Vasogenic Edema IVIG Therapy
Ethical standards and patient consent
We declare that all human and animal studies have been approved by the University of Pittsburgh Medical Center Institutional Review Board and have therefore been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. We declare that the patient’s representative gave informed consent prior to inclusion in this study.
Conflict of interest
We declare that we have no conflict of interest.