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Balanced steady-state free-precession MR imaging for measuring pulsatile motion of cerebellar tonsils during the cardiac cycle: a reliability study

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Abstract

Introduction

Assessment of the motion of the cerebellar tonsils is of interest in diseases affecting the CSF flow at the foramen magnum. Cardiac-gated balanced steady-state free-precession technique, which has recently been shown to demonstrate the pulsatile motion of neural structures, appears well suited to allow direct measurement of craniocaudal translation of cerebellar tonsils during the cardiac cycle. Our aim was to assess the intra-observer and inter-observer variability in the assessment of tonsillar motion utilizing this technique.

Methods

We retrospectively identified 44 patients who had undergone MR imaging with cine TrueFISP sequence, as a part of CSF flow study. Two neuroradiologists independently assessed the images. The tonsillar pulsatility was subjectively characterized into none, minimal, and marked categories after review of the images on a cine loop. For patients with identifiable tonsillar motion, the maximal extent of translation of the inferior edge of the cerebellar tonsil was directly measured. Both readers repeated the measurements after a minimum interval of 2 weeks. Intra- and inter-observer variability was characterized by calculating the kappa statistics.

Results

The intra-observer agreement for subjective assessment of tonsillar pulsatility was near perfect while the inter-observer agreement was substantial. A good intra- and inter-observer correlation was also seen for the objective measurements of the tonsillar motion. A good correlation was found between the subjective categorization of the tonsillar pulsatility and the objective measurements.

Conclusion

Steady-state balanced free-precession MR imaging technique allows for a reproducible subjective and objective assessment of tonsillar pulsatility.

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Conflict of interest

We declare that we have no conflict of interest.

Author information

Correspondence to Aseem Sharma.

Electronic supplementary material

Below is the link to the electronic supplementary material.

Sagittal cine TrueFISP images viewed in a cine loop in three different patients. Each cine loop consists of 25 images obtained in the same location in the sagittal plane during the cardiac cycle. The images have been zoomed to highlight the change in the tonsillar position during the cardiac cycle. Based on the subjective perception of the extent of tonsillar translation, the tonsillar pulsatility was graded as 0 (video 1), 1 (video 2), and 2 (video 3) by both the readers.

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Video 1

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Video 2

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Video 3

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Sharma, A., Parsons, M.S. & Pilgram, T.K. Balanced steady-state free-precession MR imaging for measuring pulsatile motion of cerebellar tonsils during the cardiac cycle: a reliability study. Neuroradiology 54, 133–138 (2012). https://doi.org/10.1007/s00234-011-0861-3

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Keywords

  • Cerebrospinal fluid
  • Chiari malformation
  • Syringomyelia
  • Magnetic resonance imaging