Neuroradiology

, Volume 54, Issue 1, pp 25–33 | Cite as

The entire dural sinus tree is compressed in patients with idiopathic intracranial hypertension: a longitudinal, volumetric magnetic resonance imaging study

  • Axel Rohr
  • Jan Bindeballe
  • Christian Riedel
  • Andreas van Baalen
  • Thorsten Bartsch
  • Lutz Doerner
  • Olav Jansen
Diagnostic Neuroradiology

Abstract

Introduction

The objective of this study was to explore the volumetric alterations of dural sinuses in patients with idiopathic intracranial hypertension (IIH).

Methods

Standardized cranial magnetic resonance imaging (MRI) was used in 17 patients prior to and following treatment of IIH and in seven controls. Magnetic resonance venographies (MRV) were employed for (a) judgement of circumscript dural sinus stenoses and (b) computation of sinus volumes. Cross-sectional areas (CSA) of the superior sagittal sinuses (SSS) were measured on T2-weighted images. Results of the initial MRIs were compared to those on follow-up MRIs and to results of controls.

Results

Stenoses of the transverse sinuses (TS) resulting in cranial venous outflow obstruction (CVOO) were present in 15/17 (88%) patients, normalizing in 7/15 cases (47%) after treatment of IIH. CVOO was not detected in the control group. Segmentation of MRV revealed decreased dural sinus volumes in patients with IIH as compared to controls (P = 0.018). Sinus volumes increased significantly with normalization of intracranial pressure independent from disappearing of TS stenoses (P = 0.007). The CSA of the SSS were normal on the initial MRIs of patients with IIH and increased on follow-up after treatment (P < 0.001). However, volumetries displayed overlap in patients and controls.

Conclusions

Patients with IIH not only exhibit bilateral stenoses of the TS as has been reported, but volume changes of their entire dural sinus system also occur. The potential etiopathological and diagnostic roles of these changes are discussed.

Keywords

Intracranial hypertension Pseudotumor cerebri Dural sinus Volumetry 

Notes

Conflict of interest

We declare that we have no conflict of interest.

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Copyright information

© Springer-Verlag 2011

Authors and Affiliations

  • Axel Rohr
    • 1
  • Jan Bindeballe
    • 1
  • Christian Riedel
    • 1
  • Andreas van Baalen
    • 2
  • Thorsten Bartsch
    • 3
  • Lutz Doerner
    • 4
  • Olav Jansen
    • 1
  1. 1.Department of NeuroradiologyUniversity Clinic of Schleswig-Holstein Campus KielKielGermany
  2. 2.Department of NeuropediatricsUniversity Clinic of Schleswig-Holstein Campus KielKielGermany
  3. 3.Department of NeurologyUniversity Clinic of Schleswig-Holstein Campus KielKielGermany
  4. 4.Department of NeurosurgeryUniversity Clinic of Schleswig-Holstein Campus KielKielGermany

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