Neuroradiology

, Volume 52, Issue 10, pp 883–891

The angioarchitectural factors of the cerebral developmental venous anomaly; can they be the causes of concurrent sporadic cavernous malformation?

  • Yoo Jin Hong
  • Tae-Sub Chung
  • Sang Hyun Suh
  • Chul Hwan Park
  • Geetanjali Tomar
  • Kwon Duk Seo
  • Keung Sik Kim
  • In Kook Park
Diagnostic Neuroradiology

DOI: 10.1007/s00234-009-0640-6

Cite this article as:
Hong, Y.J., Chung, TS., Suh, S.H. et al. Neuroradiology (2010) 52: 883. doi:10.1007/s00234-009-0640-6

Abstract

Introduction

The aim of this paper was to evaluate the angioarchitectural factors that can induce concurrent cavernous malformation (CM) in the territory of developmental venous anomaly (DVA).

Methods

From January 2006 to December 2007, 21 patients with 23 CMs in the territory of DVA were retrospectively analyzed (M; F = 12; 9, mean age = 53.3). Gadovist®-enhanced three-dimensional spoiled gradient-echo images on a 3 T magnetic resonance (MR) scanner were used. We investigated the presence of angioarchitectural factors: factor 1, the angulated course of curved medullary or draining vein in the distal portion of CM; factor 2, narrowing of distal draining vein; factor 3, severe medullary venous tortuosity. These were also analyzed for control group of 23 subjects (M; F = 11; 12, mean age = 46).

Results

Factor 1 was demonstrated in 22 cases (97%) and the CM occurred in a position of 90° or less of an abrupt angulated medullary or draining vein in 15 cases (65%) of the study group. Factor 2 was found in 13 cases (57%) with the diameter reduction of 50% or more in five cases. The mean ratio of diameter reduction was 0.53. Factor 3 was found in 17 cases (74%). Analyzing the independent factors, the p values for factors 1 and 3 were <.05, i.e., statistically significant. If combination of more than two factors was present, the p values for all the combinations were <0.05, i.e., statistically significant.

Conclusion

Anatomical angioarchitectural factors might be the key factors in causing concurrent sporadic CM within the territory of DVA by causing disturbance of blood flow.

Keywords

Cavernous malformation Developmental venous anomaly Flow disturbance Angioarchitectural factor 

Abbreviations

CM

cavernous malformation

DVA

developmental venous anomaly

SPGR

spoiled gradient-echo

MPRs

multiplanar reconstructions

Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Yoo Jin Hong
    • 1
  • Tae-Sub Chung
    • 1
  • Sang Hyun Suh
    • 1
  • Chul Hwan Park
    • 1
  • Geetanjali Tomar
    • 1
  • Kwon Duk Seo
    • 2
  • Keung Sik Kim
    • 1
  • In Kook Park
    • 3
  1. 1.Department of Radiology, Gangnam Severance HospitalYonsei University College of MedicineSeoulSouth Korea
  2. 2.Department of Neurology, Gangnam Severance HospitalYonsei University College of MedicineSeoulSouth Korea
  3. 3.Department of Life SciencesDongguk UniversityGyungjuSouth Korea

Personalised recommendations