, 52:61 | Cite as

Influence of carotid artery stenting on cognitive function

  • Iris Quasar Grunwald
  • Panagiotis Papanagiotou
  • Wolfgang Reith
  • Martin Backens
  • Tilman Supprian
  • Maria Politi
  • Verena Vedder
  • K. Zercher
  • B. Muscalla
  • Anton Haass
  • Christoph M. Krick
Functional Neuroradiology



There have only been a few studies on cognitive changes in patients with carotid occlusive disease, and the results of these show major discrepancies in the extent to which treatment affects neuropsychological function. We sought to clarify these discrepancies by evaluating the effects of carotid artery stenting (CAS) on the cognitive function.


Forty-one asymptomatic CAS patients were administered a test battery of neuropsychological tests measuring cognitive speed and memory function before and 3 months after the procedure. A control group was also evaluated. To test for thromboembolic lesions, diffusion-weighted imaging was used.


CAS led to a significant increase in cognitive speed (p < 0.001) but did not afford any change in memory function. This was regardless of the degree or side of stenosis or patient age or gender.


CAS significantly improved functions that involve cognitive speed. Earlier studies did not differentiate between speed and memory tests and thus might have missed these changes. Further studies correlating changes in brain perfusion with increase in cognitive speed are needed.


Arterial stenosis Stenting Cognitive function 


Conflict of interest statement

We declare that we have no conflict of interest.


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Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Iris Quasar Grunwald
    • 1
    • 4
  • Panagiotis Papanagiotou
    • 1
  • Wolfgang Reith
    • 2
    • 3
  • Martin Backens
    • 1
  • Tilman Supprian
    • 2
    • 3
  • Maria Politi
    • 1
  • Verena Vedder
    • 1
  • K. Zercher
    • 1
  • B. Muscalla
    • 2
    • 3
  • Anton Haass
    • 2
    • 3
  • Christoph M. Krick
    • 2
    • 3
  1. 1.Department for Diagnostic and Interventional NeuroradiologySaarland University ClinicHomburgGermany
  2. 2.Clinic for NeurologySaarland University ClinicHomburgGermany
  3. 3.Clinic for Psychiatry and PsychotherapySaarland University ClinicHomburgGermany
  4. 4.Department of NeuroradiologyHomburgGermany

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