Advertisement

Neuroradiology

, Volume 51, Issue 5, pp 347–356 | Cite as

Effects of failed commissuration on the septum pellucidum and fornix: implications for fetal imaging

  • Paul D. Griffiths
  • Ruth Batty
  • Dan A. J. Connolly
  • Michael J. Reeves
Paediatric Neuroradiology

Abstract

In the previous article, we considered the normal appearances of the midline stuctures of the brain as they appear on high-resolution magnetic resonance imaging. In this article, we discuss the effects of failed commissuration on the midline structures. We highlight some of the misconceptions of this process that may lead to misdiagnosis of agenesis of the corpus callosum in utero.

Keywords

Magnetic resonance imaging Corpus callosum Septum pelucidum Fornix Failed commissuration 

Notes

Conflict of interest statement

We declare that we have no conflict of interest.

References

  1. 1.
    Taylor M, David AS (2005) Agenesis of the corpus callosum: a United Kingdom series of 56 cases. J Neurol Neurosurg Psychiatry 25(13):1181–1187Google Scholar
  2. 2.
    Fratelli N, Papageorghiou AT, Prefumo F, Homfray T, Thilaganathan B (2007) Outcome of prenatally diagnosed agenesis of the corpus callosum. Prenat Diagn 27:512–517. doi: 10.1002/pd.1719 PubMedCrossRefGoogle Scholar
  3. 3.
    Rapp B, Perrotin F, Marret H, Sembely-Taveau C, Lansac J, Body G (2002) Value of fetal cerebral MRI for the prenatal diagnosis and prognosis of corpus callosum agenesis. J Gynecol Obstet Biol Reprod (Paris) 2(1):173–182Google Scholar
  4. 4.
    Whitby EH, Paley MNJ, Sprigg A, Rutter S, Davies NP, Wilkinson ID, Griffiths PD (2004) Outcome of 100 singleton pregnancies with suspected brain abnormalities diagnosed on ultrasound and investigated by in utero MR imaging. Br J Obs Gynae 111:784–792Google Scholar
  5. 5.
    Glenn OA, Barkovich AJ (2006) MRI of the fetal brain and spine: an increasingly important tool in prenatal diagnosis (part 2). AJNR Am J Neuroradiol 27(9):1807–1814PubMedGoogle Scholar
  6. 6.
    Griffiths PD, Batty R, Reeves M, Connolly DAJ (2009) Imaging the corpus callosum, septum pellucidum and fornix in children: normal anatomy and variations of normality. Neuroradiology (in press).Google Scholar
  7. 7.
    Barkovich AJ (1995) Congenital malformations of the brain and skull. In: Barkovich AJ (ed) Pediatric neuroimaging 2nd edition. Raven, New York, pp 177–275Google Scholar
  8. 8.
    Rakic P, Yakovlev PI (1968) Development of the corpus callosum and cavum septi in man. J Comp Neurol 32:45–72. doi: 10.1002/cne.901320103 CrossRefGoogle Scholar
  9. 9.
    Raybaud C (2003) Classification of commissural disorders (callosal agenesis and related disorders). Riv Neuroradiologia 16(2):179–182Google Scholar
  10. 10.
    Barkovich AJ (1990) Apparent atypical callosal dysgenesis. AJNR Am J Neuroradiol 11:333–340PubMedGoogle Scholar
  11. 11.
    Sadler TW (1990) Central Nervous System Chapter 20. In: Sadler TW (ed) Langman's Medical Embryology 6th edition. Williams and Wilkins, Baltimore, p 376Google Scholar

Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Paul D. Griffiths
    • 1
    • 3
  • Ruth Batty
    • 1
    • 2
  • Dan A. J. Connolly
    • 1
    • 2
  • Michael J. Reeves
    • 1
  1. 1.Academic Unit of RadiologyUniversity of SheffieldSheffieldUK
  2. 2.Department of RadiologySheffield Teaching Hospitals NHS Foundation TrustSheffieldUK
  3. 3.Academic Unit of Radiology, C FloorRoyal Hallamshire HospitalSheffieldUK

Personalised recommendations