, Volume 51, Issue 5, pp 337–345 | Cite as

Imaging the corpus callosum, septum pellucidum and fornix in children: normal anatomy and variations of normality

  • Paul D. Griffiths
  • Ruth Batty
  • Michael J. Reeves
  • Dan J. A. Connolly
Paediatric Neuroradiology


The midline structures of the supra-tentorial brain are important landmarks for judging if the brain has formed correctly. In this article, we consider the normal appearances of the corpus callosum, septum pellucidum and fornix as shown on MR imaging in normal and near-normal states.


Brain development Magnetic resonance imaging Corpus callosum Septum pellucidum Fornix 


Conflict of interest statement

We declare that we have no conflict of interest.


  1. 1.
    Standring S. Ventricular system and cerebrospinal fluid (chapter 16). In: Gray’s Anatomy 39th edition. S Standring (Ed) Elsevier 2005;287–294Google Scholar
  2. 2.
    Aldur MM, Berker M, Celik HM, Sargon MF, Ugur Y, Dagdeviren A (2002) The ultrastructure and immunohistochemistry of the septum pellucidum in a case of thalamic low grade astrocytoma with review of literature. Neuroanatomy 1:7–11Google Scholar
  3. 3.
    Harding BN (1992) Malformations of the nervous system. In: Hume Adams J, Duchen LW (eds) Greenfield’s neuropathology, 5th edn. Edward Arnold, London, pp 521–638Google Scholar
  4. 4.
    Carpenter MB (1991) Olfactory pathways, hippocampal formation and the amygdale. In: Carpenter MB (ed) Core text of neuroanatomy, 4th edn. Williams and Wilkins, Baltimore, pp 361–384Google Scholar
  5. 5.
    Rakic P, Yakovlev PI (1968) Development of the corpus callosum and cavum septi in man. J Comp Neurol 32:45–72CrossRefGoogle Scholar
  6. 6.
    Mott SH, Bodensteiner JB, Allan WC (1992) The cavum septi pellucidi in term and preterm newborn infants. J Child Neurol. 7(1):35–38PubMedCrossRefGoogle Scholar
  7. 7.
    Schwidde JT (1952) Incidence of cavum septi pellucidi and cavum vergae in 1032 human brains. Archives of Neurology and Psychiatry 67:625–632Google Scholar
  8. 8.
    Degreef G, Lantos G, Bogerts B, Ashtari M, Lieberman J (1992) Abnormalities of the septum pellucidum on MR scans in first episode schizophrenic patients. American Journal of Neuroradiology 13(3):835–840PubMedGoogle Scholar
  9. 9.
    Nopoulos PC, Giedd JN, Andreasen NC, Rapoport JL (1998) Frequency and severity of enlarged cavum septi pellucidi in childhood-onset schizophrenia. American Journal of Psychiatry 155(8):1074–1079PubMedGoogle Scholar
  10. 10.
    Bodensteiner JB, Schaefer GB, Craft JM (1998) Cavum septi pellucidi and cavum vergae in normal and developmentally delayed populations. J Child Neurology 13(3):120–121CrossRefGoogle Scholar

Copyright information

© Springer-Verlag 2009

Authors and Affiliations

  • Paul D. Griffiths
    • 1
    • 3
  • Ruth Batty
    • 2
  • Michael J. Reeves
    • 1
  • Dan J. A. Connolly
    • 2
  1. 1.Academic Unit of RadiologyUniversity of SheffieldSheffieldUK
  2. 2.Department of RadiologySheffield Teaching Hospitals NHS Foundation TrustSheffieldUK
  3. 3.Academic Unit of RadiologyC Floor, Royal Hallamshire HospitalSheffieldUK

Personalised recommendations