Narrow CSF space at high convexity and high midline areas in idiopathic normal pressure hydrocephalus detected by axial and coronal MRI
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The aim of this study was to determine the performance of axial and coronal magnetic resonance imaging (MRI) in detecting the narrowing of the cerebrospinal fluid (CSF) space at the high convexity and high midline areas, which is speculated to be one of the clinical characteristics of idiopathic normal pressure hydrocephalus (iNPH).
We retrospectively examined axial and coronal T1-weighted images of 14 iNPH patients and 12 age-matched controls. The narrowness of the CSF space at the high convexity/midline was blindly evaluated by five raters using a continuous confidence rating scale for receiver operating characteristic (ROC) analysis.
Axial and coronal imaging accurately determined the presence of the narrow cisterns/sulci at the high convexity/midline and was capable of predicting probable/definite iNPH with a high degree of accuracy. there were also no significant differences in the detection of this finding between the axial and coronal images.
Both axial and coronal T1-weighted MRI can detect the narrow CSF space at the high convexity/midline accurately and may therefore facilitate clinicians in choosing a management strategy for iNPH patients.
KeywordsIdiopathic normal pressure hydrocephalus Magnetic resonance imaging Subarachnoid space Receiver operating characteristic analysis
This work was partly supported by a Research Grant from the Ministry of Health, Labour and Welfare of Japan (2005-Nanchi-17) and by a Grant-in-Aid for Advanced Medical Science Research from the Ministry of Education, Culture, Sports, Science and Technology of Japan.
Conflict of interest statement
We declare that we have no conflict of interest.
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