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Neuroradiology

, Volume 48, Issue 10, pp 695–702 | Cite as

Meningiomas with conventional MRI findings resembling intraaxial tumors: can perfusion-weighted MRI be helpful in differentiation?

  • Bahattin Hakyemez
  • Nalan Yildirim
  • Cüneyt Erdoðan
  • Hasan Kocaeli
  • Ender Korfali
  • Mufit Parlak
Diagnostic Neuroradiology

Abstract

Introduction

To investigate the contribution of perfusion-weighted MRI to the differentiation of meningiomas with atypical conventional MRI findings from intraaxial tumors.

Methods

We retrospectively analyzed 54 meningiomas, 12 glioblastomas and 13 solitary metastases. We detected 6 meningiomas with atypical features on conventional MRI resembling intraaxial tumors. The regional cerebral blood flow (rCBV) ratios of all tumors were calculated via perfusion-weighted MRI. The signal intensity-time curves were plotted and three different curve patterns were observed. The type 1 curve resembled normal brain parenchyma or the postenhancement part was minimally below the baseline, the type 2 curve was similar to the type 1 curve but with the postenhancement part above the baseline, and the type 3 curve had the postenhancement part below the baseline accompanied by widening of the curve. Student’s t-test was used for statistical analysis.

Results

On CBV images meningiomas were hypervascular and the mean rCBV ratio was 10.58±2.00. For glioblastomas and metastatic lesions, the rCBV ratios were 5.02±1.40 and 4.68±1.54, respectively. There was a statistically significant difference in rCBV ratios between meningiomas and glioblastomas and metastases (P<0.001). Only one of the meningiomas displayed a type 2 curve while five showed a type 3 curve. Glioblastomas and metastases displayed either a type 1 or a type 2 curve. None of the meningiomas showed a type 1 curve and none of the glioblastomas or metastases showed a type 3 curve.

Conclusion

Differentiating meningiomas with atypical conventional MRI findings from malignant intraaxial tumors can be difficult. Calculation of rCBV ratios and construction of signal intensity-time curves may contribute to the differentiation of meningiomas from intraaxial tumors.

Keywords

Magnetic resonance Perfusion imaging Brain tumors Meningioma 

Notes

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Copyright information

© Springer-Verlag 2006

Authors and Affiliations

  • Bahattin Hakyemez
    • 1
    • 2
  • Nalan Yildirim
    • 1
  • Cüneyt Erdoðan
    • 1
  • Hasan Kocaeli
    • 3
  • Ender Korfali
    • 3
  • Mufit Parlak
    • 1
  1. 1.Department of RadiologyUludag University Medical SchoolBursaTurkey
  2. 2.Department of RadiologyBursa State HospitalBursaTurkey
  3. 3.Department of NeurosurgeryUludag University Medical SchoolBursaTurkey

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