, Volume 47, Issue 12, pp 895–902 | Cite as

Analysis of the brain-stem white-matter tracts with diffusion tensor imaging

  • N. Salamon
  • N. Sicotte
  • J. Alger
  • D. Shattuck
  • S. Perlman
  • U. Sinha
  • H. Schultze-Haakh
  • G. Salamon
Diagnostic Neuroradiology


The authors have reviewed the diffusion tensor imaging (DTI) of the brain stem in 19 subjects, consisting of 15 normal volunteers and four multi-system atrophy patients. The study was performed with 1.5 T MRI scanners. DTI was correlated with an automated program allowing superposition of the structural anatomy. Axial, sagittal, and coronal images demonstrated major white-matter fibers within the brain stem, including cortico-spinal tracts, transverse pontine fibers, and medial lemniscus. Smaller fibers, such as medial longitudinal fascicles and central tegmental tracts are difficult to visualize. To identify the anatomical orientation of the brain stem, white-matter fibers will help us understand the different functional disease processes, and DTI will play an important role for the evaluation of the different white matter fibers in the brain stem.


Diffusion tensor imaging Brain stem White-matter fiber 



This work is supported by NIH grant RO1 EY 015311-011.


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Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  • N. Salamon
    • 1
  • N. Sicotte
    • 2
    • 3
  • J. Alger
    • 1
    • 2
  • D. Shattuck
    • 2
  • S. Perlman
    • 3
  • U. Sinha
    • 1
  • H. Schultze-Haakh
    • 4
  • G. Salamon
    • 1
  1. 1.Department of RadiologyUniversity of California at Los AngelesLos AngelesUSA
  2. 2.Department of Human Brain Mapping CenterUniversity of California at Los AngelesLos AngelesUSA
  3. 3.Department of NeurologyUniversity of California at Los AngelesLos AngelesUSA
  4. 4.Siemens Medical SystemIselinUSA

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