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Neuroradiology

, Volume 48, Issue 2, pp 78–83 | Cite as

Imaging features of copper deficiency myelopathy: a study of 25 cases

  • Neeraj KumarEmail author
  • J. Eric Ahlskog
  • Christopher J. Klein
  • John D. Port
Diagnostic Neuroradiology

Abstract

Acquired copper deficiency presents with a spastic gait and sensory ataxia. Spinal cord magnetic resonance imaging (MRI) in patients with copper deficiency myelopathy may show increased T2 signal, most commonly in the dorsal midline cervical and thoracic cord. These imaging findings may be reversible with normalization of serum copper. The clinical and imaging picture is very similar to the subacute combined degeneration seen in patients with vitamin B12 deficiency. Neuroradiologists should consider this possibility when a long segment of symmetric dorsal spinal cord T2-hyperintensity is identified.

Keywords

Copper deficiency Myelopathy Magnetic resonance Cord signal 

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Copyright information

© Springer-Verlag 2005

Authors and Affiliations

  • Neeraj Kumar
    • 1
    • 3
    Email author
  • J. Eric Ahlskog
    • 1
  • Christopher J. Klein
    • 1
  • John D. Port
    • 2
  1. 1.Department of NeurologyMayo ClinicRochesterUSA
  2. 2.Department of RadiologyMayo ClinicRochesterUSA
  3. 3.RochesterUSA

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