, Volume 46, Issue 5, pp 339–350 | Cite as

Diffusion tensor imaging of the brain: review of clinical applications

  • P. C. SundgrenEmail author
  • Q. Dong
  • D. Gómez-Hassan
  • S. K. Mukherji
  • P. Maly
  • R. Welsh
Diagnostic Neuroradiology


We review the theoretical background to diffusion tensor imaging (DTI) and some of its commoner clinical applications, such as cerebral ischemia, brain maturation and traumatic brain injury. We also review its potential use in diseases such as epilepsy, multiple sclerosis, and Alzheimer’s disease. The value of DTI in the investigation of brain tumors and metabolic disorders is assessed.


Magnetic resonance imaging Diffusion tensor imaging Brain 



We wish to say a special thank you to Professor Thomas Chenevert, Department of Radiology, University of Michigan Hospitals, for valuable comments and support in the preparation of this manuscript.


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Copyright information

© Springer-Verlag 2004

Authors and Affiliations

  • P. C. Sundgren
    • 1
    Email author
  • Q. Dong
    • 1
  • D. Gómez-Hassan
    • 1
  • S. K. Mukherji
    • 1
  • P. Maly
    • 1
  • R. Welsh
    • 1
  1. 1.Department of RadiologyUniversity of Michigan Health SystemAnn ArborUSA

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