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Neuroradiology

, Volume 45, Issue 6, pp 381–385 | Cite as

Contrast enhancement in Lhermitte–Duclos disease of the cerebellum: correlation of imaging with neuropathology in two cases

  • L. Spaargaren
  • P. Cras
  • M. A. M. Bomhof
  • S. T. Lie
  • A. M. de Barsy
  • P. H. Croese
  • J. L. J. M. Teepen
  • V. H. J. M. Duwel
  • J. W. Van Goethem
  • O. Ozsarlak
  • L. van den Hauwe
  • A. M. De Schepper
  • P. M. Parizel
Diagnostic Neuroradiology

Abstract

Lhermitte–Duclos disease (LDD), also known as dysplastic gangliocytoma, is a rare cerebellar lesion. It has long been regarded as avascular. We report two patients with surgically proven LDD in whom contrast enhancement was observed on MRI. Neuropathological examination revealed proliferation of veins. We suggest that peripheral enhancement of LDD probably reflects vascular proliferation of the cerebellar venous draining system, and should be considered part of the imaging features of LDD.

Key words

Lhermitte–Duclos disease Dysplastic gangliocytoma Contrast enhancement 

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Copyright information

© Springer-Verlag 2003

Authors and Affiliations

  • L. Spaargaren
    • 1
  • P. Cras
    • 2
  • M. A. M. Bomhof
    • 3
  • S. T. Lie
    • 4
  • A. M. de Barsy
    • 5
  • P. H. Croese
    • 6
  • J. L. J. M. Teepen
    • 7
  • V. H. J. M. Duwel
    • 8
  • J. W. Van Goethem
    • 1
  • O. Ozsarlak
    • 1
  • L. van den Hauwe
    • 9
  • A. M. De Schepper
    • 1
  • P. M. Parizel
    • 1
  1. 1.Department of Radiology, Universitair Ziekenhuis AntwerpenUniversity of AntwerpEdegemBelgium
  2. 2.Department of Neurology, Universitair Ziekenhuis AntwerpenUniversity of AntwerpEdegemBelgium
  3. 3.Department of NeurologyAmphia Ziekenhuis BredaBredaThe Netherlands
  4. 4.Department of NeurosurgeryElisabeth Ziekenhuis TilburgTilburgThe Netherlands
  5. 5.Department of NeurologyAlgemeen Ziekenhuis KLINABrasschaatBelgium
  6. 6.Department of NeurosurgeryAlgemeen Ziekenhuis KLINABrasschaatBelgium
  7. 7.Department of NeuropathologyElisabeth Ziekenhuis TilburgTilburgThe Netherlands
  8. 8.Department of PathologyAlgemeen Ziekenhuis KLINABrasschaatBelgium
  9. 9.Department of RadiologyAlgemeen Ziekenhuis KLINABrasschaatBelgium

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