Neuroradiology

, Volume 44, Issue 4, pp 314–318 | Cite as

High signal of the striatum in sporadic Creutzfeldt-Jakob disease: sequential change on T2-weighted MRI

  • A. Uemura
  • T. O'uchi
  • T. Sakamoto
  • N. Yashiro
Diagnostic Neuroradiology

Abstract.

The object of this study is to describe the sequential change of high signal of the striatum on T2-weighted MRI in sporadic Creutzfeldt-Jakob disease (CJD). Three cases of autopsy-proven sporadic CJD and a total of 18 serial MR images are included in this study. The degree of high signal of the striatum on T2-weighted MRI was evaluated by two neuroradiologists and divided into four grades by mutual agreement. Initial MRI of all three cases showed a slightly high signal of the bilateral striatum, and the conspicuity of the high signal became more prominent as the disease progressed. In each case the pathological change of striatum and globus pallidus was compared with the high signal on the last MR image.

Creutzfeldt-Jakob disease High-signal T2-weighted MRI Striatum 

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Copyright information

© Springer-Verlag 2002

Authors and Affiliations

  • A. Uemura
    • 1
  • T. O'uchi
    • 1
  • T. Sakamoto
    • 1
  • N. Yashiro
    • 1
  1. 1.Department of Radiology, Kameda Medical Center, 929 Higashi-cho, Kamogawa, Chiba 296-8602, JapanJapan

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