The Journal of Membrane Biology

, Volume 211, Issue 2, pp 65–79

COPI-mediated Transport

Topical Review

DOI: 10.1007/s00232-006-0859-7

Cite this article as:
Béthune, J., Wieland, F. & Moelleken, J. J Membrane Biol (2006) 211: 65. doi:10.1007/s00232-006-0859-7


COPI-coated vesicles are protein and liquid carriers that mediate transport within the early secretory pathway. In this Topical Review, we present their main protein components and discuss current models for cargo sorting. Finally, we describe the striking similarities that exist between the COPI system and the two other characterized types of vesicular carriers: COPII- and clathrin-coated vesicles.


Membrane transport Membrane transport mechanisms SNARE biochemistry 

Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  1. 1.Biochemie Zentrum, University of HeidelbergHeidelbergGermany

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