European Journal of Clinical Pharmacology

, Volume 74, Issue 9, pp 1185–1186 | Cite as

Prevalence of use of antipsychotic drugs in the elderly in Catalonia

  • Carmen Asensio
  • Núria Escoda
  • Mònica Sabaté
  • Pere Carbonell
  • Pilar López
  • Joan-Ramon Laporte
Letter to the Editor

Montastruc et al. [1] reported an annual prevalence of use of antipsychotic drugs (APs) of 2.0% in the general population and 3.6% among those ≥ 65 years old in France.

The use of AP in the elderly is of concern. Systematic reviews by regulatory agencies [2, 3] have concluded that the use of APs for the treatment of aggression and psychotic symptoms in elderly patients with dementia increases mortality by twofold. In 2008, the European national regulatory agencies recommended limiting the use of APs to patients not responding to other interventions during the shortest possible period and to reconsider their prescription at every follow-up visit, with close patient follow-up [4].

In spite of these recommendations, in Catalonia between 2008 and 2013, the consumption by the general population of AP increased from 9.8 to 11.9 defined daily doses (DDD) per 1000 inhabitants and per day [5].

We examined the use of APs among the elderly in the Catalan Health Service (CHS) prescription claims...


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Fundació Institut Català de Farmacologia, WHO Collaborating Centre for Research & Training in PharmacoepidemiologyUniversitat Autònoma de Barcelona, HU Vall d’HebronBarcelonaSpain
  2. 2.Gerència de Farmàcia i del Medicament, Servei Català de la SalutBarcelonaSpain
  3. 3.Servei de Farmacologia ClínicaHU Vall d’HebronBarcelonaSpain

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