Tendinopathy after ofloxacin ear drops
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Fluoroquinolone antibiotics are commonly prescribed. These drugs are known to increase the risk of tendon injury, including rupture . We report an unusual case of fluoroquinolone-induced tendinopathy considering the route of administration.
A 58-year-old man, with no relevant medical history, had experienced a first episode of tendinopathy in 2002 after taking five pills of ofloxacin 200 mg associated with corticosteroids for otitis. The complete recovery took 1 year.
In October 2014, the patient consulted an ear/nose/throat specialist, who prescribed ofloxacin ear drops (1.5 mg per dose instilled in each ear bid) for bilateral external otitis. No canal or tympanic injury was seen. No other drug was taken. One hour after the third instillation, the patient experienced pain in both feet then pain in the Achilles tendons, knees, shoulders and wrists. The symptoms were similar to those presented in 2002. Ofloxacin was withdrawn after three instillations. The symptoms worsened over the...
KeywordsFluoroquinolone Ofloxacin Achilles Tendon External Otitis Pharmacovigilance Database
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