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European Journal of Clinical Pharmacology

, Volume 70, Issue 11, pp 1325–1332 | Cite as

Should nurses or clinical pharmacists perform medication reconciliation? A randomized controlled trial

  • Trine Aag
  • Beate Hennie GarciaEmail author
  • Kirsten K. Viktil
Clinical Trial

Abstract

Purpose

To study differences in outcomes of medication reconciliation (MR) when performed by clinical pharmacists compared to nurses.

Methods

201 patients (21–92 years) admitted to the Department of Cardiology at the University Hospital of North Norway, autumn 2012, were randomized into a pharmacist group (PG) and a nurse group (NG). The nurses and the pharmacists were trained for performing the MR process by an independent clinical pharmacist. Medication discrepancies (MDs) were discussed with the physicians. Time spent during the MR was recorded. An independent expert group rated clinical relevance of the MDs retrospectively.

Results

At least one MD was identified in 78 % and 84 % of patients in PG and NG, respectively (P = 0.269) with a mean number of MDs per patient 3.1 (SD 2.1) and 2.8 (SD 2.2), respectively (P = 0.528). Mean time spent/patient on the MR process was 22.9 min (SD 11.6) in the PG and 32.2 min (SD 20.3) in the NG (P < 0,001). Physicians agreed significantly more often to act upon the MDs presented by pharmacists compared to nurses (P = 0.001). The expert group finally assessed 48 % and 49 % of the MDs to be of the clinical relevance in the PG and the NG, respectively.

Conclusions

By applying a structured method for MR, a small however not statistically significant difference in identified MDs between nurses and clinical pharmacists was revealed. The pharmacists spent significantly less time than the nurses, and physicians agreed significantly more often with the pharmacist that action should be taken on the MDs. This is important in the discussion of who to perform MR.

Keywords

Medication reconciliation randomized controlled trial clinical pharmacist nurse integrated medicines management (IMM) 

Notes

Acknowledgement

We thank the personnel and patients at the Department of Cardiology at the University hospital of North Norway for all help and collaboration, especially the tree nurses that participated; Jeanette Robertsen, Jenny Vesterhus and Katrine Vollen. We thank MD Richard Slubowski for the help in validating the English-Norwegian translation of clinical relevance criteria and the expert group for rating clinical relevance. We thank Sykehusapotekene i Midt-Norge HF for teaching, help and collaboration regarding the IMM methodology and IMM tools.

Conflict of interest

The authors declare that they have no conflicts of interest to disclose.

Supplementary material

228_2014_1741_MOESM1_ESM.docx (34 kb)
ESM 1 (DOCX 33 kb)

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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Trine Aag
    • 1
  • Beate Hennie Garcia
    • 1
    • 2
    Email author
  • Kirsten K. Viktil
    • 3
    • 4
  1. 1.Hospital Pharmacy of North Norway TrustTromsøNorway
  2. 2.Department of Pharmacy, Faculty of Health SciencesUniversity of TromsøTromsøNorway
  3. 3.School of PharmacyThe Faculty of Mathematics and Natural SciencesOsloNorway
  4. 4.Diakonhjemmet Hospital PharmacyOsloNorway

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