European Journal of Clinical Pharmacology

, Volume 69, Issue 3, pp 743–745 | Cite as

ACE inhibitors and ribavirin-associated cough: a common undefined predisposing factor?

  • Laura Milazzo
  • Dario Cattaneo
  • Stefania Cheli
  • Laurenzia Ferraris
  • Elisa Colella
  • Emilio Clementi
  • Cristina Gervasoni
Letter to the Editors

References

  1. 1.
    Hoofnagle JH, Seeff LB (2006) Peginterferon and ribavirin for chronic hepatitis C. N Engl J Med 355:2444–2451PubMedCrossRefGoogle Scholar
  2. 2.
    Brok J, Gluud LL, Gluud C (2005) Effects of adding ribavirin to interferon to treat chronic hepatitis C infection: a systematic review and meta-analysis of randomized trials. Arch Intern Med 165:2206–2212PubMedCrossRefGoogle Scholar
  3. 3.
    Dicpinigaitis PV, Weiner FR (2011) Chronic cough associated with interferon⁄ribavirin therapy for hepatitis C. J Clin Pharm Ther 36:416–418PubMedCrossRefGoogle Scholar
  4. 4.
    Izzo JL Jr, Weir MR (2011) Angiotensin-converting enzyme inhibitors. J Clin Hypertens 13:667–675CrossRefGoogle Scholar
  5. 5.
    Grilo A, Saez-Rosas MP, Santos-Morano J, Sánchez E, Moreno-Rey C, Real LM, Ramírez-Lorca R, Sáez ME (2011) Identification of genetic factors associated with susceptibility to angiotensin-converting enzyme inhibitors-induced cough. Pharmacogenet Genomics 21:10–17PubMedCrossRefGoogle Scholar
  6. 6.
    Mas S, Gassò P, Alvarez S, Ortiz J, Sotoca JM, Francino A, Carne X, Lafuente A (2011) Pharmacogenetic predictors of angiotensin-converting enzyme inhibitor-induced cough: the role of ACE, ABO, and BDKRB2 genes. Pharmacogenet Genomics 21:531–538PubMedCrossRefGoogle Scholar
  7. 7.
    Morello J, Rodrıguez-Novoa S, Jimenez-Nacher I, Soriano V (2008) Usefulness of monitoring ribavirin plasma concentrations to improve treatment response in patients with chronic hepatitis C. J Antimicrob Chemother 62:1174–1180PubMedCrossRefGoogle Scholar
  8. 8.
    Fellay J, Thompson AJ, Ge D, Gumbs CE, Urban TJ, Shianna KV, Little LD, Qiu P, Bertelsen AH, Watson M, Warner A, Muir AJ, Brass C, Albrecht J, Sulkowski M, McHutchison JG, Goldstein DB (2010) ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C. Nature 464:405–408PubMedCrossRefGoogle Scholar
  9. 9.
    Thompson AJ, Fellay J, Patel K, Tillmann HL, Naggie S, Ge D, Urban TJ, Shianna KV, Muir AJ, Fried MW, Afdhal NH, Goldstein DB, McHutchison JG (2010) Variants in the ITPA gene protect against ribavirin-induced hemolytic anemia and decrease the need for ribavirin dose reduction. Gastroenterology 139:1181–1189PubMedCrossRefGoogle Scholar
  10. 10.
    D’Avolio A, Ciancio A, Siccardi M, Smedile A, Baietto L, Simiele M, Marucco DA, Cariti G, Calcagno A, de Requena DG, Sciandra M, Cusato J, Troshina G, Bonora S, Rizzetto M, Di Perri G (2012) Inosine triphosphatase polymorphisms and ribavirin pharmacokinetics as determinants of ribavirin-associate anemia in patients receiving standard anti-HCV treatment. Ther Drug Monit 34:165–170PubMedCrossRefGoogle Scholar
  11. 11.
    Irwin RS, Baumann MH, Bolser DC, Boulet LP, Braman SS, Brightling CE, Brown KK, Canning BJ, Chang AB, Dicpinigaitis PV, Eccles R, Glomb WB, Goldstein LB, Graham LM, Hargreave FE, Kvale PA, Lewis SZ, McCool FD, McCrory DC, Prakash UB, Pratter MR, Rosen MJ, Schulman E, Shannon JJ, Smith Hammond C, Tarlo SM (2006) Diagnosis and management of cough executive summary: ACCP evidence-based clinical practice guidelines. Chest 129 [1 Suppl]:1–23SCrossRefGoogle Scholar
  12. 12.
    Geppetti P, Patacchini R, Nassini R, Materazzi S (2010) Cough: the emerging role of the TRPA1 channel. Lung 188(Suppl 1):S63–S68PubMedCrossRefGoogle Scholar
  13. 13.
    Yeo WW, Chadwick IG, Kraskiewicz M, Jackson PR, Ramsay LE (1995) Resolution of ACE inhibitor cough: changes in subjective cough and responses to inhaled capsaicin, intradermal bradykinin and substance-P. Br J Clin Pharmacol 40:423–429PubMedGoogle Scholar

Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Laura Milazzo
    • 1
  • Dario Cattaneo
    • 2
  • Stefania Cheli
    • 2
  • Laurenzia Ferraris
    • 1
  • Elisa Colella
    • 1
  • Emilio Clementi
    • 2
    • 3
  • Cristina Gervasoni
    • 1
  1. 1.Department of Infectious DiseasesLuigi Sacco University HospitalMilanItaly
  2. 2.Unit of Clinical PharmacologyLuigi Sacco University HospitalMilanItaly
  3. 3.Eugenio Medea Scientific InstituteBosisio PariniItaly

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