European Journal of Clinical Pharmacology

, Volume 66, Issue 4, pp 427–428 | Cite as

Possible hepatotoxic effect of rooibos tea: a case report

  • Marjatta Sinisalo
  • Anna-Liisa Enkovaara
  • Kari T. Kivistö
Letter to the Editors

References

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    Joubert E, Gelderblom WC, Louw A, de Beer D (2008) South African herbal teas: Aspalathus linearis. Cyclopia spp. and Athrixia phylicoides—a review. J Ethnopharmacol 119:376–412CrossRefPubMedGoogle Scholar
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    McKay DL, Blumberg JB (2007) A review of the bioactivity of South African herbal teas: rooibos (Aspalathus linearis) and honeybush (Cyclopia intermedia). Phytother Res 21:1–16CrossRefPubMedGoogle Scholar
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    Marnewick JL, Joubert E, Swart P, Van Der Westhuizen F, Gelderblom WC (2003) Modulation of hepatic drug metabolizing enzymes and oxidative status by rooibos (Aspalathus linearis) and honeybush (Cyclopia intermedia), green and black (Camellia sinensis) teas in rats. J Agric Food Chem 51:8113–8119CrossRefPubMedGoogle Scholar
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    Matsuda K, Nishimura Y, Kurata N, Iwase M, Yasuhara H (2007) Effects of continuous ingestion of herbal teas on intestinal CYP3A in the rat. J Pharmacol Sci 103:214–221CrossRefPubMedGoogle Scholar
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    Ulicná O, Greksák M, Vancová O, Zlatos L, Galbavý S, Bozek P, Nakano M (2003) Hepatoprotective effect of rooibos tea (Aspalathus linearis) on CCl4-induced liver damage in rats. Physiol Res 52:461–466PubMedGoogle Scholar

Copyright information

© Springer-Verlag 2010

Authors and Affiliations

  • Marjatta Sinisalo
    • 1
    • 2
  • Anna-Liisa Enkovaara
    • 1
    • 2
  • Kari T. Kivistö
    • 1
    • 2
  1. 1.Department of Internal MedicineTampere University HospitalTampereFinland
  2. 2.Department of Pharmacological Sciences, Medical SchoolUniversity of TampereTampereFinland

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