European Journal of Clinical Pharmacology

, Volume 63, Issue 8, pp 809–811 | Cite as

Indapamide-induced hyperparathyroidism: a case report

  • Miguel Debono
  • Ritwik Banerjee
Letter to the Editors


Hypercalcaemia is a common metabolic abnormality and is often a clue to the presence of unsuspected illness. Hyperparathyroidism is a common cause of hypercalcaemia. The hypercalcaemia usually is discovered during a routine serum chemistry profile. Hyperparathyroidism is mainly caused by a parathyroid adenoma but other aetiologies for high parathyroid hormone levels exist, one of which has been suggested to be the use of thiazide diuretics [1]. Thiazide diuretics have been described to cause hypercalcaemia through different mechanisms [7, 8]. Our experience supports the fact that even thiazide-like diuretics may induce hyperparathyroidism as we report the case of a gentleman on indapamide. This drug, increasingly being used for the treatment of hypertension [2], has never been reported to cause this side effect.

Case report

A 75-year-old gentleman was referred by his general practitioner to an endocrine speciality clinic in November 2005 after being found to be suffering from...


Hyperparathyroidism Thiazide Primary Hyperparathyroidism Perindopril Parathyroid Adenoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag 2007

Authors and Affiliations

  1. 1.Department of Diabetes and EndocrinologyLuton and Dunstable Hospital NHS Foundation TrustLutonUK

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