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Calcified Tissue International

, Volume 67, Issue 1, pp 37–40 | Cite as

Ultrasonographic, Axial, and Peripheral Measurements in Female Patients with Benign Hypermobility Syndrome

  • J.  Nijs
  • E.  Van Essche
  • M.  De Munck
  • J.  Dequeker
Article

Abstract.

Twenty-five female Caucasians, aged 19–57 years, with the hypermobility syndrome had bone density measurements using established noninvasive techniques such as dual X-ray absorptiometry (DXA), single photon absorptiometry (SPA), heel ultrasound (US), and peripheral computed tomography (pQCT) acquisitions of the radius. As a group, comparisons of the different bone indices with the corresponding age-matched reference population resulted in normal z-scores for the arial densities, however, values for the volumetric total and cortical bone at the radius measured by pQCT were significantly lower than expected (P < 0.0001). Spinal and femoral bone density results were significant after correction for body mass index (BMI). This cross-sectional study shows that the benign hypermobility syndrome patients have lowered t-scores for data reflecting bone structure and bone strength as measured with US and the tomographic technique.

Key words: Hypermobility syndrome — Bone density — pQCT — Heel ultrasound — Fracture risk. 

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Copyright information

© Springer-Verlag New York Inc. 2000

Authors and Affiliations

  • J.  Nijs
    • 1
  • E.  Van Essche
    • 1
  • M.  De Munck
    • 1
  • J.  Dequeker
    • 1
  1. 1.Arthritis and Metabolic Bone Disease Research Unit, K.U. Leuven, U.Z. Pellenberg, Weligerveld 1,B-3212 Pellenberg, BelgiumBelgium

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